Histological and Histomorphometric Analysis of the Bone–Screw Interface in the Mandibular Body After Using a 2.0-mm Miniplate System: An Experimental Study in Dogs

Release of metals from osteosynthesis implants as a method for identification: post-autopsy histopathological and ultrastructural forensic study

“…The release of metal from osteosynthesis implants used in treatment (especially of traumatic fractures) has been studied in animals [3,8,9], in clinical dentistry and in maxillofacial surgery [2, 4-6, 8, 10-13, 20]. In the latter, various studies have also looked into its possible application in forensic odontology [18,19], suggesting not only the well-established role in the identification of corpses when metal implants are found in situ but also innovative methods based on bioengineering techniques [22], computerised virtual facial reconstructions [23] and 2D-3D superimposition techniques [24].…”

“…biomaterials designed to be included in a biological system and to support or replace an anatomic function [1,2], are used in the treatment of bone fractures; their application can provide a temporary surgical fixation of bones, removed once the fracture has repaired, or a permanent, irremovable fixation. The study of interaction between these structures and human tissues had the aim to establish any harmful long-term metabolic effects, mostly on animal samples [3][4][5][6][7][8][9] and, on humans, in the areas of maxillofacial and orthodontic surgery [10][11][12][13]. In forensic work, studies generally focus on autopsy cases where the presence of metal implants still in situ can provide important information, especially with respect to identification [14].…”

Assessment of double 2.0 osteosynthesis bone plates at the inferior border of the mandible as the sole method of fixation for the treatment of mandibular fracture

“…The plates in this study were fixed bicortically at the inferior border of the mandible as recommended by Dos Santos et al [11], who reported, in an experimental study of mongrel dogs, that miniplates adapted to the alveolar processes were fixed monocortically, whereas miniplates placed near the mandible base were fixed bicortically.…”

“…In an experimental study in mongrel dogs, it was suggested that miniplates adapted to the alveolar processes were fixed monocortically, whereas miniplates placed near the mandible base were fixed bicortically [11].…”

Análise histológica e histométrica do processo de reparo ósseo em osteotomia de corpo mandibular e interface entre tecido ósseo e parafusos após o uso do sistema de fixação interna biodegradável de 2,0mm. Estudo piloto em cães

“…Tecido ósseo imaturo não foi observado entre as bordas ósseas criadas pela osteotomia. Estas características histológicas também foram observadas em um estudo prévio, no qual um sistema de FI baseado em titânio foi utilizado com a mesma metodologia(DOS SANTOS et al, 2007).Neste período de tempo, as respostas teciduais não foram suficientes para promover a união óssea na área de osteotomia.No período de 18 semanas, entretanto, as bordas ósseas criadas pela osteotomia foram completamente conectadas por tecido ósseo neoformado. Adicionalmente, nos três terços analisados, este tecido ósseo exibiu grande quantidade de espaços medulares preenchidos por um tecido conjuntivo altamente vascularizado.…”