Histological and Biochemical Evaluations of Decellularized Meniscus Tissues using Sonication Treatment System

Abstract

Meniscus plays fundamental roles in the knee mechanisms and functions but injuries happen in meniscus have poor healing ability that requires great interventions. Tissue engineered scaffolds serve as one of the interventions to regenerate the required tissue to treat early degenerative joint disease. The purpose of this research is to examine the effectiveness of sonication treatment system in complete cellular components removal with preserved extracellular matrix (ECM) compositions in meniscus tissues through histological and biochemical evaluations. Meniscus tissues