Histological Ageing of Bruises in Lambs and Calves

McCausland, I.P.; Dougherty, Ryan J.

doi:10.1111/j.1751-0813.1978.tb00322.x

Cited by 23 publications

(13 citation statements)

References 10 publications

(5 reference statements)

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“…Controlled studies in large animals have suggested a progression of cellular infiltrates from neutrophils, to macrophages, to other mesenchymal elements (fibroblasts, endothelial cells) [12], although even in these carefully controlled settings with the application of a mathematical model, only broad conclusions could be discerned ( e.g . less than 20 hours versus 1-3 days) [10].…”

Section: Introductionmentioning

confidence: 99%

The Role of the Iron Stain in Assessing Intracranial Hemorrhage

Castellani¹,

Mojica²,

Perry³

2016

TONEUJ

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Abstract:The timing of the breakdown of red blood cells and organization of hemorrhage has significance in the catabolism of heme and the processing of iron, but also has a practical application in terms of assigning, or attempting to assign, a time course with respect to traumatic events (e.g. contusions and hemorrhages). Attempts to date contusions, however, have generally been unsuccessful by macroscopic observation, whereas the microscopic observations provide broad data but are also anatomically imprecise as a function of time. Intracranial lesions are of particular significance with respect to the timing of organizing hemorrhage given the acute, and often life-threatening nature of the hemorrhages, and the medicolegal investigation into potential crimes. Of concern is that the Prussian Blue reaction for iron, a relatively straightforward histochemical reaction that has been in use for over 150 years, is sometimes suggested as a diagnostic test for chronicity. Therefore, this study examined the utility of the Prussian Blue iron stain in living patients with intracranial hemorrhages and well-defined symptom onset, to test whether the presence of Prussian Blue reactivity could be correlated with chronicity. It was found that out of 12 cases with intracranial hemorrhage, eight cases showed at least focal iron reactivity. The duration from symptom onset to surgery in those eight cases ranged from < 24 hours to more than 3 days. Of those cases with no iron reactivity, the duration from symptom onset to surgery ranged from < 24 hours to six days. In conclusion, the Prussian Blue reaction was unreliable as an indicator of timing in intracranial hemorrhage. The use of the Prussian blue reaction as an independent indicator of chronicity is therefore not valid and can be misleading. Caution is indicated when employing iron staining for timing purposes, as its only use is to highlight, as opposed to identify, pre-existing lesions. With respect to brain lesions, the Prussian blue reaction should not be used in place of the clinical timing of the neurologic decline, or clinical data that is otherwise more accurate and less susceptible to false positive results.

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Section: Introductionmentioning

confidence: 99%

The Role of the Iron Stain in Assessing Intracranial Hemorrhage

Castellani¹,

Mojica²,

Perry³

2016

TONEUJ

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“…Putting ice on a new injury may cause a similar affect in slowing bruise resolution and altering bruise appearance in humans. Also, the color progression of bruising was found to differ between species (Hamdy, Deatherage, & Shinowara, 1956; Langlois & Gresham, 1991; McCausland & Dougherty, 1978). …”

Section: Factors Affecting Bruise Appearancementioning

confidence: 98%

Can one accurately date a bruise? State of the science

Nash

Sheridan

2009

Journal of Forensic Nursing

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Forensic nursing experts and other health professionals often testify regarding the injuries women and men receive from violence. Bruise discoloration can provide an opportunity for health professionals to grossly estimate the age of impact and determine if it is consistent with a given reported history. However, there is much confusion in the literature and clinical practice as to the accuracy of dating bruises. This article will demonstrate that using the color of the bruise as the primary criteria to determine its age is not the best practice. The limited available research and related literature on the topic are flawed and inconsistent. Finally, recommendations will be made for future research and clinical practice.

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“…Histological methods have been developed which claim to be able to differentiate between bruises occurring at various times between 48 hours' pre-slaughter and stunning(McCausland and Dougherty, 1978) Histological methods have been developed which claim to be able to differentiate between bruises occurring at various times between 48 hours' pre-slaughter and stunning(McCausland and Dougherty, 1978) …”

mentioning

confidence: 99%

From farm to slaughter

2014

Gracey's Meat Hygiene

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Histological Ageing of Bruises in Lambs and Calves

Cited by 23 publications

References 10 publications

The Role of the Iron Stain in Assessing Intracranial Hemorrhage

The Role of the Iron Stain in Assessing Intracranial Hemorrhage

Can one accurately date a bruise? State of the science

From farm to slaughter

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