Histologic Patterns of Lymphadenopathy in the Eastern Province of Saudi Arabia

Al-Sohaibani, Mohammed; Satti, Mohamed B.; Ibrahim, Ezzeldin M.; Al-Sowayan, Saleh

doi:10.5144/0256-4947.1990.516

Cited by 10 publications

(11 citation statements)

References 26 publications

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“…Similar results are observed by others. 9,12 In this study, of the total 50 cases 23 (46%) cases are male and 27 (54%) cases are female. The female to male ratio is 1: 0.88.…”

Section: Resultsmentioning

confidence: 53%

“…The similar age incidences were shown by others. 12,15,16 Duration of lymphadenopathy is of less than 6 months in 88% cases and only in 12% cases duration of lymphadenopathy is of more than 6 months.…”

Section: Resultsmentioning

confidence: 99%

“…Lower incidence in these studies may be related to the high socio economic condition in these geographical areas. 12 Over the last decade mycobacterium infections have been shown to be on rise worldwide and in the developing countries like Bangladesh, the incidence is very high.…”

Section: Resultsmentioning

confidence: 99%

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Correlation Between FNAC and Open Biopsy in Cervical Lymhadenopathy in Children

Hossain

Amin

Siddiqui

et al. 2014

J. paediatr. surg. Bangladesh

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Background: Head and Neck region of the body has a rich network of lymphatic channel and intervening nodes. Out of total approximately 800 lymph nodes in the body about 300 are scattered in organized fashion in the neck region which are affected by various regional and systemic diseases. The conventional method of excisional biopsy is used to diagnose etiological causes of lymphadenopathy. In comparison to open surgical biopsy, FNAC is a simple, reliable and acceptable tool for the etiological diagnosis of lymphadenopathies. FNAC was first practiced by Grieg and Gray for the diagnosis of trypanosome in lymphnode in 1904. Now a day it is widely practiced in United States, United Kingdom and many other countries. In Bangladesh, many studies on FNAC are carried out and the results are highly appreciable and reliable.Methods: A prospective study for a period of 24 months was carried out on 50 patients with enlarged cervical lymph nodes from July 2003 to June 2005. During the two years study period, 56 patients with cervical lymphadenopathies were selected for FNAC and openbiopsy following certain inclusion and exclusion criteria, in the Department of Pediatric Surgery, Bangabandhu Sheikh Mujiib Medical University, Dhaka. Patients with acute lymphadenitis and lymphadenopathy due to leukaemia were excluded. Six cases were deleted from the study as smears from those revealed inadequate material and hence only 50 cases were available for study in the present series. Clinical findings, FNAC and biopsy reports were available in all the cases and were correlated with each other.Results: On biopsy, 27 cases were diagnosed as tuberculous lymphadenopathies, 15 cases as lymphoma and 8 cases as reactive changes. On FNAC, there were 2 false positive and 5 false negative cases in case of tuberculosis; 2 false positive and 1 false negative cases in lymphoma; 4 false positive and 2 false negative cases in cases with reactive hyperplasia. Sensitivity of FNAC in comparison to histopathological findings was 92.6% in case of tuberculosis; 86.7% in case of lymphoma and 50% in case of nonspecific lymphadenitis. Specificity of FNAC in comparison to histological findings was 78.3% in case of tuberculosis; 94.2% in case of lymphoma and 95.3% in case of nonspecific lymphadenitis. Accuracy of FNAC in comparison to histopathological findings was 86% in case of tuberculosis; 94% in case of lymphoma and 88% in case of reactive changes.Conclusions: The present study indicates that, FNAC is a simple, reliable and acceptable procedure for various lesions of cervical lymph nodes. It can be repeated if necessary. It also concludes that FNAC helps to confirm the clinical impression without open biopsy. Open biopsy can be avoided in many benign and malignant lesions of cervical lymph nodes. Fine needle aspiration cytodiagnosis can eliminate the need of hospitalization and surgery.DOI: http://dx.doi.org/10.3329/jpsb.v1i2.19526

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“…Similar results are observed by others. 9,12 In this study, of the total 50 cases 23 (46%) cases are male and 27 (54%) cases are female. The female to male ratio is 1: 0.88.…”

Section: Resultsmentioning

confidence: 53%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Correlation Between FNAC and Open Biopsy in Cervical Lymhadenopathy in Children

Hossain

Amin

Siddiqui

et al. 2014

J. paediatr. surg. Bangladesh

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“…Sarcoidosis is recognized throughout the world but there is a marked difference in the reported incidence from one country to another. [ 11 12 ] The prevalence of sarcoidosis in the Kingdom of Saudi Arabia is as yet unknown, but has been thought to be rare. [ 7 ] Recent studies from Saudi Arabia and other regions of the Middle East have shown that sarcoidosis has been increasingly recognized.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis in the eastern region of Saudi Arabia

Al-Khouzaie¹,

Al‐Tawfiq²,

Subhi³

2011

Ann Thorac Med

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AIM:To review a general hospital’s experience with sarcoidosis and the clinical pattern of the disease among Saudis.METHODS:A retrospective file review was carried out on all patients with a proven diagnosis of sarcoidosis in a general hospital in Eastern Saudi Arabia over a period of 11 years (1998–2008).RESULTS:Sixty-nine patients, of whom 33 cases were included in the analyses, were diagnosed to have sarcoidosis during the study period. There were 18 females and 15 males. The mean age was 44.5 years (SD 17). The most common presentations were cough (48%), dyspnea (21%), joint pain (18%), splenomegaly (12%), hepatomegaly (9%), and lymphadenopathy (5%). The biochemical analysis showed elevated calcium levels in 6% and elevated angiotensin converting enzyme (ACE) in 14 (46.7%). The tuberculin skin test was negative in all tested patients (n = 29) except one patient. The patients were classified using the modified Scadding classification system. None of the patients was in stage 0, 39.4% were in stage 1, 45% were in stage 2 and 15% were in stage 3.. The diagnosis in all patients was proven histologically. The outcome was favorable in most patients (85%), and in 6% of the patients, the course was chronic and progressive, although 66% received active treatment.CONCLUSION:Sarcoidosis does occur in native Saudis. The clinical presentation of these patients was similar to the western pattern of disease with some differences such as relative lack of cardiac, eye, parotid, and central nervous system involvement. The rarity of cardiac and central nervous system involvement was comparable with other Middle Eastern studies. Sarcoidosis, though rare in our community, should still be considered in the differential diagnosis of patients with the typical presentation after excluding tuberculosis.

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“…Its involvement of cervical lymph nodes has been known a long time as Scrofula or the Kings Evil [9]. Olu-Eddo and Omoti reported lymphadenopathy as the single commonest cause of cervical lymphadenopathy constituting 35% of cases [4], and in Saudi Arabia, Al-Sohaibani reported 28% [10]. This communication describes a huge tuberculous lymphadenopathy in an HIV seronegative patient in an uncommon location for tuberculous cervical lymphadenopathy.…”

Section: Discussionmentioning

confidence: 99%

Non-caseating submental tuberculous lymphadenopathy: A case report

Asuquo¹,

Nwagbara²,

Akpan³

et al. 2013

CRCM

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Chronic peripheral lymphadenopathy in adults is an indication of pathology of which tuberculosis is the commonest in the developing countries. Presented is a 36-year-old with a huge chronic Submental lymphadenopathy in a seronegative patient of 7 years duration. Histology revealed non-caseating tuberculosis. Tuberculosis should be considered in Submental lymphadenopathy. Despite the long duration, the absence of cold abscess, and or sinus formation may be an indication of the non-caseating tuberculous lymphadenopathy.

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Histologic Patterns of Lymphadenopathy in the Eastern Province of Saudi Arabia

Cited by 10 publications

References 26 publications

Correlation Between FNAC and Open Biopsy in Cervical Lymhadenopathy in Children

Correlation Between FNAC and Open Biopsy in Cervical Lymhadenopathy in Children

Sarcoidosis in the eastern region of Saudi Arabia

Non-caseating submental tuberculous lymphadenopathy: A case report

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