Histologic chorioamnionitis is associated with fetal growth restriction in term and preterm infants

Diet Induced Inflammation and Potential Consequences on Fetal Development

“…Similar results were reported by Williams et al who defined histologic chorioamnionitis as marked leukocyte infiltrate of placenta and showed association of HCA with markers of fetal growth restriction (birth weight, length, head circumference, weight/length ratio and Ponderal index in the lowest 5 th percentile) [16,63]. Taken together, these results suggest that evidence linking role of inflammation (chorioamnionitis) and foetal growth restriction and development is scanty, though its link with preterm delivery is relatively well established.…”

“…Reproductive tract inflammation has been widely implicated in preterm delivery (PTD), intrauterine growth restriction (IUGR), increased HIV and sexually transmissible infections (STIs) and HIV replication [61][62][63][64]. Evidence for fetal involvement with funisitis and chorionic vasculitis has been reported in chorioamnionitis [65,66].…”

Fatores de risco associados ao nascimento de recém-nascidos de muito baixo peso em uma população de baixa renda

“…Em estudo perinatal colaborativo 16 , a corioamnionite esteve presente em 6% de 43.940 partos. A freqüência aumentou com a diminuição da idade gestacional: 15% entre 28-32 semanas, 8% entre 33-36 e 5% após as 36 semanas de gestação.…”

Prediction and Diagnosis of Preterm Delivery: Review

“…Koryoamniyonit oranı, gestasyonel yaşın azalmasıyla artan şekilde 28-32. haftalar arasında %15; 33-36. haftalar arasında %8 ve 36. haftadan sonra %5'tir. 43 İnflamasyon sonucu fosfolipit membranlardan açığa çıkan araşidonik asit, fosfolipaz A2 ve prostaglandinlerin bazıları uterotonik etki göstermekte, bazıları da servikal yumuşamaya katkı da bulunmaktadır. Aynı zamanda vajinal mikroorganizmalar, her sahada >5 nötrofil varlığı ile tanımlanan inflamatuar yanıtı da başlamaktadır.…”