Histoire du foyer de la trypanosomose humaine africaine de nola en republique centrafricaine, de 1971 à 2004

M’Belesso, Pascal; koona, A Koona; Mbadingai, S; Grésenguet, Gérard; gboumbi, C Kounda; Guezza, D; Dumas, María

doi:10.4314/ajns.v27i2.55091

Cited by 2 publications

(2 citation statements)

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“…Mais une Cette flambée s'explique par la détérioration des systèmes de santé, l'abandon ou l'affaiblissement des programmes de lutte, l'instabilité sociopolitique avec les mouvements incessants de la population [2,3]. Le gouvernement a créé en 1990 le PNLTHA [5]. Ce programme a oeuvré efficacement à la stabilisation, puis à la décroissance progressive de la maladie, par l'intensification de la prospection (dépistage actif et traitement), la création des centres de traitement ambulatoire (Nola centre, commune de Bilolo) et la lutte antivectorielle, avec la pose de pièges coniques imprégnés d'insecticides [7,9].…”

Section: Discussionunclassified

Vers la maîtrise de l’endémie sommeilleuse dans le foyer de Nola-Bilolo en Centrafrique

M’Belesso¹,

Mbadingai²,

Nguembe³

2011

Bull. Soc. Pathol. Exot.

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Sleeping sickness is more prevalent in three historical regions of Central African Republic. Control measures were organized by the colonial authorities through health services to fight against this disease and other major diseases. Multivariate analysis and the government helped in controlling the disease in the focus of Nola-Bilolo, which was formerly hyperendemic. The authors report the results of the control measures that resulted in the extinction of the disease in this outbreak. This is a retrospective study from 1991 to 2008, and the data were collected from the National Program to fight against human African trypanosomiasis in Bangui and in the diagnostic and treatment center of Nola. It was highly endemic, with more than 300 cases recorded in the year 1991. The average number of cases was 200.8 per year between 1992 and 1998. Less than 50 cases per year were recorded from 2000 to 2006, and no cases have been detected since 2007. 69.35% of the patients were actively screened. 5,000 conical deltamethrin-impregnated traps (Gouteux and Lancien) had been used in 15 districts in the city of Nola and 46 surrounding villages by 20 trappers fully supported by the program. This is an example of regular active mass screening. Systematic treatment of detected cases and well-conducted vector control measures give hope to the affected populations to live peacefully in order to contribute to the development of their country.

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Section: Discussionunclassified

Vers la maîtrise de l’endémie sommeilleuse dans le foyer de Nola-Bilolo en Centrafrique

M’Belesso¹,

Mbadingai²,

Nguembe³

2011

Bull. Soc. Pathol. Exot.

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“…Numerous epidemiological surveys carried out in this outbreak have shown that it has remained very active, often with epidemic outbreaks [4] [5] [6]. Historical data on human African trypanosomiasis in CAR show that in 1945, the country had the sad record of 25,000 trypanosomiasis cases out of the 50,000 in French Equatorial Africa [7]. The fight against the great endemics had reduced this number to 84 patients in 1968 for all outbreaks [8].…”

Section: Introductionmentioning

confidence: 99%

Epidemiological, Clinical and Evolutionary Aspects of Human African Trypanosomiasis in Children in Nola

Mejiozem,

Tékpa,

Nazita

et al. 2024

OJPed

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Background: Human African trypanosomiasis (HAT) occurs in three historical foci in the Central African Republic. Objective: To describe the morbimortality of childhood HAT in rural Central African Republic with the aim of early management. Methods: Descriptive and analytic cross-sectional study conducted from January 1, 2017 to March 30, 2018 at Nola prefectural hospital. This study was included all children seen as outpatients and/or hospitalized in the pediatric wards, in whom the diagnosis of HAT was confirmed. Statistical analysis was performed using Epi-info software. Results: Forty children were included from Bilolo (60%), Nola (30%) and Salo (10%). The sex ratio was 0.66 with a median age of 8.65 ± 12.48 years. Fever (82.5%), nocturnal insomnia (75%), daytime somnolence (67.5%), headache (65%), polyarthralgia (62.5%), convulsions 52.5% (n = 21), tremor (27.5%), trypanidism (7.5%) and delirium (2.5%) were the main functional signs. Examination signs were adenopathy (52.5%), paresthesia (30%), decreased cutaneousabdominal reflexes (25%) and osteoarticular reflexes (17.5%), hyperesthesia (20%), extrapyramidal hypertonia (15%) and depression (2.5%). The children were in the lymphatic-blood phase in 65% of cases, and meningoencephalitis in 35%. Pentamidine was administered in 65% of cases. Four children died and 6 had neurological sequelae. There was an association between age under 5, Bilolo's focus, the children's history and the severity of the disease. Age under 5, gender, household, children's activity, history

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Histoire du foyer de la trypanosomose humaine africaine de nola en republique centrafricaine, de 1971 à 2004

Cited by 2 publications

References 1 publication

Vers la maîtrise de l’endémie sommeilleuse dans le foyer de Nola-Bilolo en Centrafrique

Vers la maîtrise de l’endémie sommeilleuse dans le foyer de Nola-Bilolo en Centrafrique

Epidemiological, Clinical and Evolutionary Aspects of Human African Trypanosomiasis in Children in Nola

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