Histoid leprosy presenting with figurate lesions: A unique and rare presentation

Histoid leprosy - A rare clinical presentation

“… 1 , 2 , 3 , 4 , 5 , 6 , 7 It presents with erythematous-brownish papules and nodules, with smooth or rarely umbilicated surface. 1 , 2 , 3 , 4 , 5 , 6 , 7 Due to its unusual clinical features, it is a challenging diagnosis. 1 , 2 , 3 , 4…”

“… 1 , 2 , 3 , 4 , 5 , 6 , 7 Due to its unusual clinical features, it is a challenging diagnosis. 1 , 2 , 3 , 4…”

“…The histoid leprosy subtype has been associated with dapsone resistance and mutations of Mycobacterium leprae strains due to inadequate treatment. 1 , 2 , 4 , 7 Currently, there is an increase in cases of the histoid form again. 1 , 2 , 3 , 4 , 5 There is an association with increased cellular and also humoral immunity, absent in lepromatous patients, increasing the number of T lymphocytes locally.…”

“… 1 , 2 , 4 , 7 Currently, there is an increase in cases of the histoid form again. 1 , 2 , 3 , 4 , 5 There is an association with increased cellular and also humoral immunity, absent in lepromatous patients, increasing the number of T lymphocytes locally. However, bacillary hyperactivity and the attempt to contain the infection, end up weakening the local immune system.…”

“…However, bacillary hyperactivity and the attempt to contain the infection, end up weakening the local immune system. 1 , 3 , 4 , 6 , 7 The lesions represent a reservoir of Mycobacterium leprae and are extremely infectious. 1 , 2 , 3 , 4 , 5 , 6 , 7 …”