Histochimie enzymatique de la muqueuse gastrique dans certaines conditions pathologiques

Teodori, U; Geñtilini, Paolo

doi:10.1159/000202220

Digestion

1965

DOI: 10.1159/000202220

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Histochimie enzymatique de la muqueuse gastrique dans certaines conditions pathologiques

U Teodori¹,

Paolo Geñtilini²

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1967

1973

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Cited by 5 publications

References 8 publications

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The enzyme histochemistry of gastric carcinoma in man

Lev

Siegel

Glass

1969

Cancer

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The histoenzymatic activity of numerous hydrolytic and oxidative enzymes was determined in cryostat sections of fresh tissues obtained surgically from 15 patients with gastric carcinoma, 18 normal subjects, and 28 patients with chronic atrophic gastritis and intestinal metaplasia. The average enzyme activity in malignant cells was less than that found in intestinal metaplasia but greater than that found in normal gastric surface epithelium. Stromal inflammatory cells exhibited activity for acid phosphatase and B‐glucuronidase, and smooth muscle fibers stained for the lactic and succinic dehydrogenases and DPN and TPN diaphorases. These elements and the islands of intestinal metaplasia found in malignancy‐bearing stomachs may contribute to the elevated levels of certain enzymes found biochemically in gastric secretions and tissue homogenates from patients with gastric carcinoma. Lactic dehydrogenase and the diaphorases were found in many carcinomata whereas succinic dehydrogenase was found in only one case. This pattern may be related to the high glycolytic rate characteristic of most malignant tumors, including those arising in the stomach.

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The enzyme histochemistry of gastric carcinoma in man

Lev

Siegel

Glass

1969

Cancer

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Etude histologique et histochimique des l�sions induites au niveau du poumon de souris par un carcinog�ne: le N-nitroso-N methylurethane

Caulet¹,

Pluot²

1970

Z Krebs-forsch

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Untersuchungen über Muster und Verteilung von Enzymen in der Schleimhaut des menschlichen Gastrointestinaltraktes

Klein¹,

Drube²,

Hansen³

1967

Klin Wochenschr

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Histochimie enzymatique de la muqueuse gastrique dans certaines conditions pathologiques

Cited by 5 publications

References 8 publications

The enzyme histochemistry of gastric carcinoma in man

The enzyme histochemistry of gastric carcinoma in man

Etude histologique et histochimique des l�sions induites au niveau du poumon de souris par un carcinog�ne: le N-nitroso-N methylurethane

Untersuchungen über Muster und Verteilung von Enzymen in der Schleimhaut des menschlichen Gastrointestinaltraktes

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