Histochemical observation of lectin-binding patterns in Paget's disease.

Nakamura, Takaaki; Fukushima, Shoji; Ito, Nobuyuki; Takai, Yoshiaki; Tatemoto, Yukihiro; Mori, Masahiko

doi:10.1267/ahc.19.451

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1988

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“…The present study revealed EMA to be mostly restricted to the focal and basal/parabasal types of Paget's disease. EMA is a glycoprotein which probably has affinity for lectins, and Paget cells showed strong lectin bindings (8,21,26), which is compatible with the presence of EMA in those cells.…”

Section: Discussionmentioning

confidence: 53%

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Immunohistochemical identification of keratin, involucrin, and epithelial membrane antigen in Paget's disease.

Sumitomo

Tatemoto

Tanimura

et al. 1988

Acta Histochem. Cytochem

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Section: Discussionmentioning

confidence: 53%

“…Histochemically, Paget cells contain PAS-positive polysaccharides and bind lectins such as PNA, DAB, and SBA which are specific for galactose and N-acetyl-galactosamine (8,21,27). Recently, it has been reported that Paget cells contain particular types of cytokeratins different from those of epidermis (16,17).…”

Section: Immunohistochemicalmentioning

confidence: 99%