Histidine-Bound Dinitrosyl Iron Complexes: Antioxidant and Antiradical Properties
Konstantin B. Shumaev,
Olga V. Kosmachevskaya,
Elvira I. Nasybullina
et al.
Abstract:Dinitrosyl iron complexes (DNICs) are important physiological derivatives of nitric oxide. These complexes have a wide range of biological activities, with antioxidant and antiradical ones being of particular interest and importance. We studied the interaction between DNICs associated with the dipeptide L-carnosine or serum albumin and prooxidants under conditions mimicking oxidative stress. The ligands of these DNICs were histidine residues of carnosine or His39 and Cys34 in bovine serum albumin. Carnosine-bo… Show more
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