Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images
Weiqin Zhao,
Zhuo Liang,
Xianjie Huang
et al.
Abstract:Histology images, with low cost, are unleashing great power of predicting cellular phenotypes in tissue, thanks to the emerging spatial transcriptomics serving as annotations. Recent efforts aimed to predict individual gene expression, suffering from low accuracy and high variability, while no methods are tailored to predict cell types - the most critical phenotype. Here, we present Hist2Cell, a Vision Graph- Transformer framework, to resolve fine-grained cell types directly from histology images and further c… Show more
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