“…Similar elevations in FSH concentrations have been observed in middleaged rats (28). The cause of the rise in FSH concentrations has been studied in both The Hypothalamus, Follicle Development, and the Ovulatory Surge of LH follicles nor undergo ovulation [for review, see (19)l. Virtually nothing is known about the factors that regulate proliferation, that govern the organization of cells into discrete follicles, or that influence the extent of cell loss during the early embryonic stage.…”