Hippocrates, on the Infection of the Lower Respiratory Tract among the General Population in Ancient Greece

Tsoucalas, Gregory; Σγάντζος, Μάρκος

doi:10.4172/2327-5146.1000272

Cited by 5 publications

(5 citation statements)

References 6 publications

(4 reference statements)

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“…He invented a device reminiscent of a modern inhaler in terms of its structure. It consisted of a container and a cover with an opening, to which a reed was attached enabling inhalation (4,14,20,20,26).…”

Section: Devices Used For Nebulizationmentioning

confidence: 99%

The history, current state and perspectives of aerosol therapy

et al. 2021

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Nebulization is a very effective method of drug administration. This technique has been popular since ancient times when inhalation of plants rich in tropane alkaloids with spasmolytic and analgesic effects was widely used. Undoubtedly, the invention of anasthesia in the 19th century had an influence on the development of this technique. It resulted in the search for devices that facilitated anasthesia such as pulveriser or hydronium. From the second half of the 21st century, when the first DPI and MDI inhalers were launched, the constant development of aerosol therapy has been noticed. This is due to the fact that nebulization, compared with other means of medicinal substance application (such as oral and intravenous routes of administration), is safer and it exhibits a positive dose/efficacy ratio connected to the reduction of the dose. It enables drugs administration through the lung and possesses very fast onset action. Therefore, various drugs prescribed in respiratory diseases (such as corticosteroids, β-agonists, anticholinergics) are present on the market in a form of an aerosol.

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Section: Devices Used For Nebulizationmentioning

confidence: 99%

The history, current state and perspectives of aerosol therapy

et al. 2021

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“…6 In his collection of works, Corpus Hippocraticum, Hippocrates (considered the Father of Modern Medicine) used fever patterns and sputum purulence to characterize and diagnose lower respiratory tract infections ranging from pneumonia to tuberculosis. 7 As technology advanced, we moved into a pathogen detection era of ID diagnostics. The first successful Gram stain and bacterial cultures were performed in the late 1800s, 8 and the more recent use of antigen detection tests and polymerase chain reaction continued to increase our ability to identify more microbes more quickly than culture.…”

Section: Primer On Infectious Disease Diagnosticsmentioning

confidence: 99%

Host-Based Diagnostics for Acute Respiratory Infections

Ross

Zick²,

Tsalik

2019

Clinical Therapeutics

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Purpose: The inappropriate use of antimicrobials, especially in acute respiratory infections (ARIs), is largely driven by difficulty distinguishing bacterial, viral, and noninfectious etiologies of illness. A new frontier in infectious disease diagnostics looks to the host response for disease classification. This article examines how host responseebased diagnostics for ARIs are being used in clinical practice, as well as new developments in the research pipeline. Methods: A limited search was conducted of the relevant literature, with emphasis placed on literature published in the last 5 years (2014e2019). Findings: Advances are being made in all areas of host responseebased diagnostics for ARIs. Specifically, there has been significant progress made in single protein biomarkers, as well as in various "omics" fields (including proteomics, metabolomics, and transcriptomics) and wearable technologies. There are many potential applications of a host responseebased approach; a few key examples include the ability to discriminate bacterial and viral disease, presymptomatic diagnosis of infection, and pathogen-specific host response diagnostics, including modeling disease progression. Implications: As biomarker measurement technologies continue to improve, host responseebased diagnostics will increasingly be translated to clinically available platforms that can generate a holistic characterization of an individual's health. This knowledge, in the hands of both patient and provider, can improve care for the individual patient and help fight rising rates of antibiotic resistance. (Clin Ther.

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“…Thus the cut should have been made near the umbilicus region, or proximal to the last rib [16]. For the patient to undertake such surgical interventions, surprisingly Hippocratic medicine introduced the endotracheal intubation after anaesthesia, by using a thin stannum (tin) tube through the larynx, for the lung to attract "pneuma" (Greek: πνεύμα, pneuma ≈ air = the vital force of the soul) [17,18].…”

Section: Hepatic Surgery In Ancient Greecementioning

confidence: 99%

Promethean and Tityean hepatic regeneration, unveiling hepar's myth. Post mortem observation, surgical ascertainment, or just fiction?

Tsoucalas¹,

Kapsoritakis²,

Potamianos³

et al. 2017

J Univer Surg

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Two ancient Greek myths, the sad stories of Prometheus and Tityus, suggest that ancient Greek medico-philosophers observed hepar's ability to regenerate after a partial excision. For some, hepar was the centre of the soul and an important visceral organ for human's body homeostasis. Although facts such as war surgery, dissections, both human and animal, autopsies and abdominal surgery (hepatic abscesses and malignancies) testify that ancient Greeks had some knowledge on hepar's anatomy and physiology, there is no clear reference that they did witness the hepatic regeneration.

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Hippocrates, on the Infection of the Lower Respiratory Tract among the General Population in Ancient Greece

Cited by 5 publications

References 6 publications

The history, current state and perspectives of aerosol therapy

The history, current state and perspectives of aerosol therapy

Host-Based Diagnostics for Acute Respiratory Infections

Promethean and Tityean hepatic regeneration, unveiling hepar's myth. Post mortem observation, surgical ascertainment, or just fiction?

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