Hipoacusia e infección por el virus de la inmunodeficiencia humana. Estudio de 30 pacientes

Bango, M. Yebra; Ureta, Pablo Tutor de; García-Lomas, M. Villarreal; Castro, N. Mata; López, Fernando J. García

doi:10.1016/s0014-2565(00)70627-8

Cited by 13 publications

(1 citation statement)

References 19 publications

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“…The most notable changes include earlier treatment initiation, the use of safer and less toxic ARV drugs and the inclusion of a single, fixed-dose combination tablet taken only once-daily (OD), which may improve treatment adherence (WHO, 2013(WHO, , 2015. A variety of studies have suggested that ARVs may be ototoxic (Kakuda, 2000;Khoza-Shangase, 2011;Marra et al, 1997;Mata, Yebra, Tutor de Ureta, Villarreal, & García, 2000). However, establishing the ototoxic relationship between ARVs and auditory function is intricate due to a range of confounding variables affecting auditory function (Khoza-Shangase, 2011).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus

Millar

Joubert

Naudé

2020

South African Journal of Communication Disorders

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Background:The Human Immunodeficiency Virus (HIV) has become a global pandemic. With the improvement of antiretroviral (ARV) treatment regimens, life-expectancy of HIV-positive individuals has increased. HIV literature suggests that head and neck manifestations may be the first indication of supressed immunity. Therefore, research regarding the effects of HIV and new treatment regimens on auditory function remains a priority.Objectives: To describe the audiological characteristics and determine the prevalence of hearing loss and tinnitus in a group of HIV-positive individuals on ARV treatment residing in a rural province. Methods:The study employed a cross-sectional descriptive research design. Participants were recruited from the clinic and pharmacy waiting areas of a medical centre in a rural area of Limpopo province, South Africa. Two participant groups, an HIV-positive group (N 1 = 60) and an HIV-negative group (N 2 = 32) were included in the study. The test battery comprised a comprehensive case history and a routine audiological test battery, which included otoscopy, tympanometry and pure tone audiometry (250 Hz to 8000 Hz).Results: No statistically significant difference was found regarding the prevalence of hearing loss in the two participant groups (p = 0.709). However, the prevalence of tinnitus was significantly higher in the HIV-positive group (p = 0.05). Conclusion:The insignificant difference in the audiological test battery results found between the two participant groups may be due to improved ARV treatment regimens and management strategies employed at the medical centre. However, the increased prevalence of tinnitus in the HIV-positive group may also be attributed to the ARV regimen and/or the result of subtle damage to the auditory system, which was not identified by the current audiological test battery. More insight may be obtained about the effects of HIV on hearing by employing a longitudinal research design and inclusion of a more ototoxicity sensitive test battery.

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Section: Introductionmentioning

confidence: 99%

Prevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus

Millar

Joubert

Naudé

2020

South African Journal of Communication Disorders

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Effect of HIV Infection and Highly Active Antiretroviral Therapy on Hearing Function

Fokouo

Vokwely

Noubiap³

et al. 2015

JAMA Otolaryngol Head Neck Surg

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Manifestations of HIV in the Head and Neck

Sorensen

2010

Curr Infect Dis Rep

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The worldwide incidence of human immunodeficiency virus (HIV) is increasing. The head and neck is a primary site for numerous manifestations of HIV disease, and it is clear that one or more of these processes will eventually affect most patients. HIV-infected patients are susceptible to all of the usual problems encountered in the head and neck, and the disease poses unique and significant problems rarely encountered in the non-HIV-infected patient. These problems include otolaryngic infections, inflammatory processes, and malignancies. The institution of highly active antiretroviral medications has significantly decreased the mortality and morbidity of this disease, and has resulted in significant improvements in quality of life. However, antiretroviral therapy can also suppress widely disseminated disease in the usual locations so that the head and neck becomes the presenting anatomic site for these processes. It is important for the health care team to be aware of these problems so that early diagnosis and treatment can be provided.

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Hipoacusia e infección por el virus de la inmunodeficiencia humana. Estudio de 30 pacientes

Cited by 13 publications

References 19 publications

Prevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus

Prevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus

Effect of HIV Infection and Highly Active Antiretroviral Therapy on Hearing Function

Manifestations of HIV in the Head and Neck

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