Hipertensión portal secundaria a sarcoidosis hepática

Abstract

The etiology of hepatic granulomas varies depending on the epidemiology. In developed countries, primary biliary chol­angitis (PBC) is the main cause followed by sarcoidosis. In developing countries, it is tuberculosis. We present the case of a patient with chronic liver disease, whose anatomo­pathological diagnosis was compatible with sarcoidosis. It was a 55-year-old woman, with a history of type 2 diabe­tes (DBT), insulin-requiring and overweight. Her disease debuted with SAE, subsequently presenting HDA of vari­ceal origin. She was referred to our institution for study. Physical examination has hepatosplenomegaly and in the laboratory FAL and yGT augmented with non-reactive anti-LKM and AMA. Ultrasonography of the abdomen showed hepatosplenomegaly, without focal images. Hepatic biopsy puncture was performed, which reported numerous portal-site granulomas. The ECA dose was increased. The diagnosis of sarcoidosis was established and treatment with deflazacort was started. She presented an upper gastrointes­tinal bleeding causing her death.