2013
DOI: 10.35790/jbm.5.1.2013.2599
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Hiperbilirubinemia Pada Neonatus

Abstract: Hyperbilirubinemia is an increase of the blood bilirubin level due to physiological or non-physiologic factors, which is clinically characterized by jaundice. Bilirubin is produced in the reticuloendothelial system as the end product of heme catabolism through an oxidation-reduction reaction. Due to its hydrophobic nature, unconjugated bilirubin is carried in the plasma, tightly bound to albumin. In the liver, bilirubin is transported into hepatocytes, bound to ligandin. After being excreted to the small intes… Show more

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Cited by 9 publications
(13 citation statements)
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“…Some risk factors for neonatal jaundice are 35 to 37 weeks gestation, polycythemia such us mother's Hemoglobin (Hb), platelet count (PLT), White Blood Cell (WBC), different degrees of bilirubin with T4 levels, Thyroid Stimulating Hormone (TSH), septicemia, infants of diabetic mother, labor assisted by vacuum or forceps, labor trauma, Asian races, a history of jaundice in previous children, hemolytic causing like rhesus, ABO incompatibility and glucose-6-phosphate dehydrogenase (G6PD) deficiency, pyruvate kinase deficiency, spherocytosis congenital, Lucey-Driscoll syndrome, Crigler-Najjar disease, hypothyroid, and hemoglobinopathy and wrong breastfeeding track [11], [20], [21].…”
Section: Literature Reviewmentioning
confidence: 99%
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“…Some risk factors for neonatal jaundice are 35 to 37 weeks gestation, polycythemia such us mother's Hemoglobin (Hb), platelet count (PLT), White Blood Cell (WBC), different degrees of bilirubin with T4 levels, Thyroid Stimulating Hormone (TSH), septicemia, infants of diabetic mother, labor assisted by vacuum or forceps, labor trauma, Asian races, a history of jaundice in previous children, hemolytic causing like rhesus, ABO incompatibility and glucose-6-phosphate dehydrogenase (G6PD) deficiency, pyruvate kinase deficiency, spherocytosis congenital, Lucey-Driscoll syndrome, Crigler-Najjar disease, hypothyroid, and hemoglobinopathy and wrong breastfeeding track [11], [20], [21].…”
Section: Literature Reviewmentioning
confidence: 99%
“…The increasing number of red blood cells with any cause is also at risk for hyperbilirubinemia. Various types of infections in infants can also increase the risk of neonatal jaundice track [21]. The event of the baby jaundice can be experienced in baby in the first 24 hours of birth.…”
Section: Literature Reviewmentioning
confidence: 99%
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“…Phototherapy is recommended if the total serum bilirubin level is > 12 mg/dL in neonates aged 25-48 hours after birth, and is mandatory if the total serum bilirubin level is 15 mg/dL. 1,14 Thus, in this article, there are several aspects that are reviewed as effective parameters:…”
Section: Discussionmentioning
confidence: 99%
“…Hiperbilirubinemia adalah terjadinya peningkatan kadar bilirubin dalam darah, baik oleh faktor fisiologis maupun non fisiologis yang secara klinis menimbulkan gejala yang disebut ikterus (kuning). 1 Ikterus merupakan salah satu gejala yang umum dijumpai pada bayi baru lahir (neonatus). Kejadian ikterus sebanyak 50-52% pada bayi cukup bulan dan 80% terjadi pada bayi berat lahir rendah.…”
Section: Pendahuluanunclassified