Hip muscle strength and protection against structural worsening and poor function and disability outcomes in knee osteoarthritis

Abstract

Objective: Examine associations of hip abductor strength with (1) cartilage damage worsening in the tibiofemoral and patellofemoral compartments 2 years later, and (2) poor function and disability outcomes 5 years later. Methods: Participants had knee osteoarthritis (K/L ! 2) in at least one knee. Hip abductor strength was measured using Biodex Dynamometry. Participants underwent 3.0T MRI of both knees at baseline and 2 years later. Baseline-to-2-year cartilage damage progression, defined as any worsening of WORMS cartilage damage score, was assessed at each tibiofemoral and patellofemoral surface. LLFDI (Late-Life Function and Disability Instrument) and Chair-Stand-Rate were recorded at baseline and 5-year followup; outcomes analyzed using quintiles. Poor outcomes were defined as remaining in the same lowfunction quintiles or being in a worse quintile at 5-year follow-up. We analyzed associations of baseline hip abductor strength with cartilage damage worsening and function and disability outcomes using multivariable log-binomial models. Results: 275 knees from 164 persons [age ¼ 63.7 (SD ¼ 9.8) years, 79.3% women] comprised the structural outcome sample, and 187 persons [age ¼ 64.2 (9.7), 78.6% women] the function and disability outcomes sample. Greater baseline hip abductor strength was associated with reduced risks of baselineto-2-year medial patellofemoral and lateral tibiofemoral cartilage damage worsening [adjusted relative risks (RRs) range: 0.80e0.83) and with reduced risks of baseline-to-5-year poor outcomes for Chair-Stand-Rate and LLFDI Basic Lower-Extremity Function and Disability Limitation (adjusted RRs range: 0.91e0.94). Conclusion: Findings support a beneficial role of hip abductor strength for disease modification and for function and disability outcomes, and as a potential therapeutic target in managing knee osteoarthritis.

Hip abductor strength–based exercise therapy in treating women with moderate-to-severe knee osteoarthritis: a randomized controlled trial

“…13 A recent study from AH Chang also supported the finding that higher baseline hip abductor strength was associated with reduced risks of worsening medial patellofemoral and lateral tibiofemoral cartilage damage from baseline to two years, as well as poor function outcomes from baseline to five years. 18 Women with knee osteoarthritis were selected in this trial. Men and women with knee osteoarthritis employ different gait strategies.…”

“…16,17 Recent discoveries have supported a beneficial role of the hip abductor as a potential therapeutic target in managing knee osteoarthritis. 18 Compared with the quadriceps, research on hip abductor muscle is limited. Only a few of these studies were rated as high quality according to a recent meta-analysis.…”

WITHDRAWN: Predictive potentials of 8 muscle strength actions, KOOS-pain, and Örebro-psychosocial difficulties on self-reported activities-of-daily-life function in patients with knee osteoarthritis: an exploratory regression-based cross-sectional study

“…However, in the current chosen primary analysis, in compliance with our selection criteria and current power constraint, we decided to adjust for KOOS-pain and psychosocial difficulties. BMI was not included in the model because the strength results were normalized to body weight(91), BMI showed no discrimination in the prior study(1), and it showed moderate-high correlation with all candidate strength predictors in the current correlation matrix (e-appendix).Figure 1shows the diagram of the causal modeling of the total effect of strength on (…”

Does low back pain or leg pain in gluteus medius syndrome contribute to lumbar degenerative disease and hip osteoarthritis and vice versa? A literature review

“…Vasilevska et al and Grimaldi et al described GTPS and the iliotibial band 32,183) . Furthermore, the strength involving the hip abductors improved the prognosis of knee osteoarthritis 184) , and thus some part of knee osteoarthritis possibly attributed to GMedS.…”