Hip and Knee Section, Pathogen Factors: Proceedings of International Consensus on Orthopedic Infections

Carijo, Julia Herkenhoff; Courtney, P. Maxwell; Goswami, Karan; Groff, Hannah; Kendoff, Daniel; Matos, Juliana da Silva; Sandiford, Nemandra A; Scheper, Henk; Schmaltz, Carolina Arana Stanis; Shubnyakov, I. I.; Tan, Timothy L.; Wouthuyzen-Bakker, Marjan

doi:10.1016/j.arth.2018.09.022

Cited by 8 publications

(3 citation statements)

References 66 publications

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“…A review of tissue histology and causative micro-organisms identified from intra-operative samples confirmed that patients included in this study met MSIS criteria for PJI. For purposes of analysis, microorganisms were classified based on those generally considered to be high-virulence or low-virulence [24][25][26]. Patients were also assigned retrospectively a systemic host grade according to the McPherson staging system, in which grade A is an uncompromised host, grade B is a compromised host with one to two compromising systemic factors, and grade C is a substantially compromised host with more than two compromising systemic factors [27,28].…”

Section: Methodsmentioning

confidence: 99%

Early Peri-Prosthetic Joint Infection after Hemiarthroplasty for Hip Fracture: Outcomes of Debridement, Antibiotics, and Implant Retention

Yassin

Sharma

Butt

et al. 2020

Surgical Infections

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Section: Methodsmentioning

confidence: 99%

Early Peri-Prosthetic Joint Infection after Hemiarthroplasty for Hip Fracture: Outcomes of Debridement, Antibiotics, and Implant Retention

Yassin

Sharma

Butt

et al. 2020

Surgical Infections

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“…The type of spacer used during two-stage revision does not influence the infection eradication rate[9,10]. In contrast, characteristics of the causative microorganism do influence the chance of infection eradication after two-stage revision[11]. Resistance to commonly prescribed antibiotics is an increasing problem as well[11].…”

Section: Introductionmentioning

confidence: 99%

“…In contrast, characteristics of the causative microorganism do influence the chance of infection eradication after two-stage revision[11]. Resistance to commonly prescribed antibiotics is an increasing problem as well[11]. Bacteria such as CoNS can form a biofilm on the prosthesis that prevents elimination by host defences and antimicrobial therapy[1,12].…”

Section: Introductionmentioning

confidence: 99%

Two-stage revision arthroplasty for coagulase-negative staphylococcal periprosthetic joint infection of the hip and knee

Veltman¹,

Moojen²,

Ogtrop

et al. 2019

WJO

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BACKGROUNDPeriprosthetic joint infections (PJIs) are frequently caused by coagulase-negative Staphylococci (CoNS), which is known to be a hard-to-treat microorganism. Antibiotic resistance among causative pathogens of PJI is increasing. Two-stage revision is the favoured treatment for chronic CoNS infection of a hip or knee prosthesis. We hypothesised that the infection eradication rate of our treatment protocol for two-stage revision surgery for CoNS PJI of the hip and knee would be comparable to eradication rates described in the literature.AIMTo evaluate the infection eradication rate of two-stage revision arthroplasty for PJI caused by CoNS.METHODSAll patients treated with two-stage revision of a hip or knee prosthesis were retrospectively included. Patients with CoNS infection were included in the study, including polymicrobial cases. Primary outcome was infection eradication at final follow-up.RESULTSForty-four patients were included in the study. Twenty-nine patients were treated for PJI of the hip and fifteen for PJI of the knee. At final follow-up after a mean of 37 mo, recurrent or persistent infection was present in eleven patients.CONCLUSIONPJI with CoNS can be a difficult to treat infection due to increasing antibiotic resistance. Infection eradication rate of 70%-80% may be achieved.

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High Rate of Reinfection With New Bacteria Following One-Stage Exchange for Enterococcal Periprosthetic Infection of the Knee: A Single-Center Study

Roßmann

Minde

Citak

et al. 2021

The Journal of Arthroplasty

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Hip and Knee Section, Pathogen Factors: Proceedings of International Consensus on Orthopedic Infections

Cited by 8 publications

References 66 publications

Early Peri-Prosthetic Joint Infection after Hemiarthroplasty for Hip Fracture: Outcomes of Debridement, Antibiotics, and Implant Retention

Early Peri-Prosthetic Joint Infection after Hemiarthroplasty for Hip Fracture: Outcomes of Debridement, Antibiotics, and Implant Retention

Two-stage revision arthroplasty for coagulase-negative staphylococcal periprosthetic joint infection of the hip and knee

High Rate of Reinfection With New Bacteria Following One-Stage Exchange for Enterococcal Periprosthetic Infection of the Knee: A Single-Center Study

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