Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral cancers
Mohammad Javad Kamali,
Mohammad Salehi,
Mehrnaz Mostafavi
et al.
Abstract:A significant portion of human cancers are caused by oncoviruses (12%–25%). Oncoviruses employ various strategies to promote their replication and induce tumourigenesis in host cells, one of which involves modifying the gene expression patterns of the host cells, leading to the rewiring of genes and resulting in significant changes in cellular processes and signalling pathways. In recent studies, a specific mode of gene regulation known as circular RNA (circRNA)‐mediated competing endogenous RNA (ceRNA) networ… Show more
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