Highly stable spherical shaped and blue photoluminescent cyclodextrin-coated tellurium nanocomposites prepared by in situ generated solvated electrons: a rapid green method and mechanistic and anticancer studies

Abstract

Highly stable blue photoluminescent Tellurium nanocomposites (Te NCs) coated with a molecular assembly of α-cyclodextrin (α-CD) have been prepared by the use of in situ generated solvated electrons (e_sol^ꟷ) in...

Solvated electron-induced synthesis of cyclodextrin-coated Pd nanoparticles: mechanistic, catalytic, and anticancer studies

“…The deconvolution of the core level spectrum of O 1s resulted in three peaks centred at 530.4, 532.3 and 533.4 eV, which could be attributed to the presence of oxide, C-O-C and H-O-C-, respectively. 41,58,59 Moving ahead, the XPS spectra of the γ-ray@Pd NPs substantiated a higher degree of oxidation on their surface as compared to the EB@Pd NPs. Fig.…”

“…The in vitro cytotoxicity of Pd NPs was assessed using the MTT colorimetric assay. 40,41 Briefly, 3 × 10 3 cells per well were plated in a 96-well plate and post 24 h of seeding; the culture medium was replaced with a medium containing either EB@Pd NPs (sphere-shaped) or γ-ray@Pd NPs (flower-shaped) in the dose range of 10, 25, 50, 100 and 500 μg mL −1 for 24 and 48 h. Following this, 100 μL of the MTT dye (0.5 mg mL −1 ) was added to each well. The plates were incubated for another 4 hours at 37 °C.…”

“…Moving ahead, the formation of an inclusionlike complex of NPs within the α-CD structure can be ruled out due to their larger average crystallite size than the host cavity of the latter (0.47-0.53 nm). 31,41,42 Some more HRTEM images at different magnification scales are provided in the ESI (see Fig. S2b-d †).…”

“…In this context, the radiation chemical approach can play a significant role in addressing all the aforementioned desirable characteristics. [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] Moreover, no external toxic reducing agent is required in this technique as a solvated electron with a reduction potential of −2.9 eV is generated in situ under a particular set of conditions. Furthermore, the morphology of the nanomaterials can be conveniently tuned by varying the experimental parameters such as the absorbed dose, dose rate, precursor concentration, nature of solvent, and host matrix.…”

“…In addition, the radiation-mediated approach offers a distinct advantage for the large-scale production of nanomaterials since the irradiation of the precursor solutions can be carried out in industrial accelerators or γ-chambers generally used for various commercial purposes such as crosslinking of polymers and sterilizing of medical kits and other items. [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] In the present study, Pd NPs have been prepared in an aqueous solution by using an electron-beam assisted approach via in vitro coating with α-cyclodextrin (α-CD). In addition to this, the NPs were synthesized using γ-ray irradiation to probe the effect of a low dose rate on their morphology, crystallinity, and surface properties.…”