2017
DOI: 10.1007/978-1-4939-6911-1_14
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Highly Sensitive Glucose Sensor Based on Organic Electrochemical Transistor with Modified Gate Electrode

Abstract: An organic electrochemical transistor (OECT) with a glucose oxidase (GOx) and poly(n-vinyl-2-pyrrolidone)-capped platinum nanoparticles (Pt NPs) gate electrode was successfully integrated with a microfluidic channel to act as a highly sensitive chip-based glucose sensor. The sensing mechanism relies on the enzymatic reaction between glucose and GOx followed by electrochemical oxidation of hydrogen peroxide (HO) produced in the enzymatic reaction. This process largely increases the electrolyte potential that ap… Show more

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Cited by 5 publications
(1 citation statement)
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“…With ion-permeable conjugated polymers utilized as the channel, analytes would affect the injection process of ions from the electrolyte to the channel by modulating the effective gate bias amplitude. 22–25 It should be stressed that the volumetric coupling between ionic and electronic charges in the channel improves the quality of recorded signals and makes OECTs powerful voltage amplifiers. 26 As a result, even a few binding events at the gate electrode can lead to significant modulations in the channel current.…”
Section: Introductionmentioning
confidence: 99%
“…With ion-permeable conjugated polymers utilized as the channel, analytes would affect the injection process of ions from the electrolyte to the channel by modulating the effective gate bias amplitude. 22–25 It should be stressed that the volumetric coupling between ionic and electronic charges in the channel improves the quality of recorded signals and makes OECTs powerful voltage amplifiers. 26 As a result, even a few binding events at the gate electrode can lead to significant modulations in the channel current.…”
Section: Introductionmentioning
confidence: 99%