Highly sensitive and stable fluorescent aptasensor based on an exonuclease III-assisted amplification strategy for ATP detection

Direct single-molecule detection of CoA-SH and ATP by the membrane proteins TMEM120A and TMEM120B

“…Researchers have proposed several sophisticated detection strategies for COA-SH and ATP, including Halo Tag protein self-labeling technology, 25 ratiometric fluorescence imaging, 26 and the use of hybrid aptamer probes. 27 While these technologies have significantly enhanced the sensitivity of COA-SH and ATP detection and effectively reduced the detection thresholds, there remains a need to optimize convenience and molecular resolution.…”