Highly selective aptamer based organic electrochemical biosensor with pico-level detection

Hydrogel‐Enabled Transfer‐Printing of Conducting Polymer Films for Soft Organic Bioelectronics

“…These unique properties of PEDOT:PSS have enabled the development of numerous advanced organic electronic devices including solar cells, light‐emitting diodes, transistors, memristors, and artificial synapses for neuromorphic computing . Recently, with the rising research trend in flexible electronics, which have offered unprecedented opportunities in revolutionizing our understanding of electronic devices, PEDOT:PSS has extended its important role in developing various flexible organic electronic devices such as organic electrochemical transistors (OECTs), an emerging tool for biosensing . However, directly manipulating and patterning PEDOT:PSS thin films on flexible substrates remain challenging because of difficulties in obtaining uniform and continuous films on soft substrates such as plastics and elastomers due to their hydrophobic nature .…”

Selective, Quantitative, and Multiplexed Surface‐Enhanced Raman Spectroscopy Using Aptamer‐Functionalized Monolithic Plasmonic Nanogrids Derived from Cross‐Point Nano‐Welding

“…As shown in Figure 2d, a distinct peak at 162 eV appears for the Apt‐AuNGs compared to a bare surface, indicating the presence of covalent AuS thiolate bonds at the surface. [ 33 ] In addition, three peaks in the N 1s region with binding energies of 399.2, 399.9, and 400.8 eV, respectively corresponding to N, NH 2 , and NH bonds from nucleotide molecules supports the formation of self‐assembled monolayers on the Au surface (Figure 2e). [ 34 ]…”

“…[ 37 ] This high level of sensitivity is attributed to the specificity and selectivity of high‐affinity aptamers ( K d = 8.3 n m for BPA, K d = 63.6 n m for tetracycline, and K d = 42.7 n m for diclofenac). [ 33 ] While Raman spectra of molecules nonspecifically bound to a plasmonic metal surface without aptamers can be still observed, the poor signal‐to‐noise ratio due to surface plasmon decay limits the sensitivity (Figure S8, Supporting Information). [ 38 ] In the case of Apt‐AuNGs, high affinity aptamers enable to capture target molecules with excellent specificity by folding into unique 3D configurations, and thus bring the target molecules closer to the plasmonic surface in the range of maximal electromagnetic signal enhancement.…”

Facile synthesis of size-controlled Fe2O3 nanoparticle-decorated carbon nanotubes for highly sensitive H2S detection

“…The synthesis of innovative nanomaterials with advanced functions is a continuously expanding issue of materials science. [1][2][3][4][5] On this subject, nanocomposites, consisting of organic and inorganic components, present improved properties originating from each component and satisfy economical and environmental challenges of the industry. [6][7][8] Metal oxidecontaining hybrid carbon nanomaterials are of great interest for diverse applications such as energy storage, catalysis, and sensor device systems.…”