Highly Selective Anionic Counterion‐based Fluorescent Sensor for Hg²⁺ by Grafted Conjugated Polyelectrolytes

Abstract

Grafted conjugated polyelectrolytes were synthesized for the first time and characterized. The polymers demonstrated properties of a convenient and efficient protocol for creating Hg(2+) sensors. The unique character of the new material comes from an anionic counterion nature with no external cofactors, and imparts high selectivity and fast detection for mercury ion in a fluorescence probe. The concept may be potentially applied to create new sensors for monitoring other ions.

Carbazole‐based conjugated polymer covalently coated Fe3O4 nanoparticle as efficient and reversible Hg2+ optical probe

“…Given the unique “signal‐amplification” effect (attributed to the transfer of excitation energy along the whole backbone), nontoxicity, and photostability, fluorescent‐conjugated polymers (CPs) have been developed rapidly in recent years as chemical and biological sensors . A series of CP‐based fluorescence turn‐off probes have been successfully synthesized with different conjugated backbones and Hg 2+ reporter substituents (such as thieno[3,4b]‐pyrazine, benzo[2,1,3]thiadiazole, thymine, and cationic quaternary ammonium). These CP‐based fluorescence turn‐off probes have shown good sensitivity and selectivity.…”

Near‐Infrared Semiconducting Polymer Brush and pH/GSH‐Responsive Polyoxometalate Cluster Hybrid Platform for Enhanced Tumor‐Specific Phototheranostics

“…In this study, a new paradigm for SPB synthesis has been first designed and successfully implemented with the SP backbone (synthesized through Stille coupling polymerization) consisting of electron‐rich (9‐hydroxy group modified fluorine (F‐OH)) and electron‐deficient (diketopyrrolopyrrole (DPP)) segments. The brushes were modified with functional groups through atom transfer radical polymerization (ATRP) reaction (Scheme S1) . Owing to the metal–thiol coordination chemistry, the widespread thiol groups within SPBs could link plenty of POM clusters.…”

“…In this study,anew paradigm for SPB synthesis has been first designed and successfully implemented with the SP backbone (synthesized through Stille coupling polymerization [13] )c onsisting of electron-rich (9-hydroxy group modified fluorine (F-OH)) and electron-deficient (diketopyrrolopyrrole (DPP)) segments.T he brushes were modified with functional groups through atom transfer radical polymerization (ATRP) reaction (Scheme S1). [14] Owing to the metalthiol coordination chemistry,t he widespread thiol groups within SPBs could link plenty of POM clusters.T hen the hybrid SPB@POM nanoplatform was formed through the self-assembly of an amphiphilic complex of POM clusters and SPBs during the DMSO dialysis (Scheme 1). Thep Hresponsive protonation of POM would drive the in situ selfassembly of SPB@POM in the acidic TME for enhanced intratumoral retention and accumulation.…”

“…The brushes were modified with functional groups through atom transfer radical polymerization (ATRP) reaction (Scheme S1). [13] Owing to the metal-thiol coordination chemistry, the widespread thiol groups within SPB could link plenty of POM clusters. Then the hybrid SPB@POM nanoplatform was formed via the self-assembly of an amphiphilic complex of POM and SPB during the DMSO dialysis (Scheme 1).…”

Star-shaped conjugated oligoelectrolyte for bioimaging in living cells

“…Structurally, conjugated polyelectrolytes (CPEs) are fluorescent macromolecules with electron-delocalized backbone and water-soluble side chains which determine the main optical properties and capability to dissolve in water for their further biological applications respectively. So far, plenty of CPEs have been obtained through palladium-catalyzed coupling reactions (Suzuki, Heck, Snogashira), such as polyfluorene (PF), poly(p-phenyleneethynylene) (PPE), polydiacetylene (PDA), poly(thiophene) (PT) [7][8][9] and so on. These materials owning relatively high photoluminescent (PL) quantum yield (QY) and good water-solubility as depicted have formed an excellent basis for chemical and biological sensors.…”