Highly Regioselective Oxygenation of C−H Bonds: Diamidomanganese Constructs with Attached Substrates as Catalyst Models

Chiral molecules containing the pyrrole framework

“…The proximity of an amino group to the ethyl groups has been known to provide a favourable environment for C-H bond activation. [68][69][70][71][72][73][74][75] A variety of metals and ligands were explored and it was found that a cationic platinum complex facilitated the transformation. Platinum complexes have previously been known 76,77 to activate methane, and sp 2 -hybridized nitrogen atoms present favourable ligands for active platinum complexes in a C-H bond activation step.…”

Achieving Site-Selectivity for C–H Activation Processes Based on Distance and Geometry: A Carpenter’s Approach

“…In a seminal work, Breslow et al reported the first example of a remote methylene C–H functionalization process through directed radical C–H abstraction, followed by elimination and ozonolysis to achieve a net remote C–H oxidation, notionally directed by an acetophenone motif through a macrocyclic hydrogen atom transfer process (Figure B) . Subsequently, Crabtree et al elegantly demonstrated the possibility of harnessing molecular recognition of substrate functionalities to achieve a manganese-catalyzed remote C–H oxidation of ibuprofen (Figure C). , In this work, the carboxylic acid on the substrate selectively binds to the carboxyl functionality on the ligand, orienting the manganese catalyst over the target C–H bond for oxidation. These pioneering examples, while elegant in design and exquisite in execution, were highly limited in their scope and applicability.…”

Transformation of 2-alkoxyimidate-1,10-phenanthroline metal (Mn2+, Co2+ and Ni2+) chlorides from bis(2-cyano-1,10-phenanthroline) metal chlorides: Syntheses, characterizations and their catalytic behavior toward ethylene oligomerization

“…Various metal complexes bearing phenanthroline derivatives were investigated as catalysts in ethylene reactivity in our group [10][11][12][13][14][15][16][17][18], and showed good catalytic activities. Manganese compounds are frequently used as catalytic precursors in epoxidation of alkenes [19][20][21], oxidation of sulfides [22,23] and hydrocarbons [24,25] as well as various asymmetric reactions [26]. Recently, a few of manganese complexes have also been reported in olefin polymerization [27][28][29][30].…”