Highly fluorescent CdTe quantum dots with reduced cytotoxicity-A Robust biomarker

Kim, Jandi; Huy, Bui The; Sakthivel, Kavitha; Choi, Hye Jung; Joo, Woo Hong; Shin, Seung Kyun; Lee, Minjae; Lee, Yong‐Ill

doi:10.1016/j.sbsr.2014.12.001

Cited by 37 publications

(12 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A widely-used QD that has found application in diverse fields is the CdTe QDs. This is due to its outstanding optical properties compared to other similar QDs, such as CdS, CdSe, ZnS, and ZnSe [ 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Rapid Synthesis of Thiol-Co-Capped-CdTe/CdSe/ZnSe Core Shell-Shell Nanoparticles: Their Optical and Structural Morphology

et al. 2021

View full text Add to dashboard Cite

CdTe QDs has been demonstrated in many studies to possess good outstanding optical and photo-physical properties. However, it has been established from literature that the toxic Cd2+ that tends to leak out into nearby solutions can be protected by less toxic ZnS or ZnSe shells leading to the synthesis of core-shells and multi-core-shells. Hence, this has allowed the synthesis of CdTe multi-core-shells to have gained much interest. The preparation of most CdTe multi-core-shells reported from various studies usually has a longer reaction time (6–24 h) in reaching their highest emission maxima. The synthesis of CdTe multi-core-shells in this study only took 35 min to obtain a highest emission maximum compared to what has been reported from the literature. CdTe multi-core-shells were synthesized by injecting 7, 14, and 21 mL each of Zn complex solution and Se ions into the reacting mixture containing CdTe core-shells (3 h) at 5 min intervals over a 35 min reaction time. The emission maxima of the MPA-TGA-CdTe multi-core-shells at 21 mL injection was recorded around 625 nm. Therefore, we are reporting the rapid synthesis of five different thiol co-capped CdTe/CdSe/ZnSe multi-core-shell QDs with the highest emission maxima obtained at 35 min reaction time.

show abstract

Section: Introductionmentioning

confidence: 99%

Rapid Synthesis of Thiol-Co-Capped-CdTe/CdSe/ZnSe Core Shell-Shell Nanoparticles: Their Optical and Structural Morphology

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Over the past two decades, considerable efforts have been made to develop QD-based fluorescence probes and sensors [15,[35][36][37][38]. In order to obtain an optimum quantum efficiency, the following stabilisers are commonly used: thioglycolic acid (TGA) [32,39,40], glutathione (GSH) [41], mercaptosuccinic acid (MSA) [42], 3-mercaptopropionic acid (MPA) [43] and L-cysteine [44,45]. CdTe QDs are known to possess a high fluorescence efficiency and good stability [46].…”

Section: Introductionmentioning

confidence: 99%

Study of Physico-Chemical Changes of CdTe QDs after Their Exposure to Environmental Conditions

Hosnedlová

Všetičková

Staňková³

et al. 2020

Nanomaterials

View full text Add to dashboard Cite

The irradiance of ultraviolet (UV) radiation is a physical parameter that significantly influences biological molecules by affecting their molecular structure. The influence of UV radiation on nanoparticles has not been investigated much. In this work, the ability of cadmium telluride quantum dots (CdTe QDs) to respond to natural UV radiation was examined. The average size of the yellow QDs was 4 nm, and the sizes of green, red and orange QDs were 2 nm. Quantum yield of green CdTe QDs-MSA (mercaptosuccinic acid)-A, yellow CdTe QDs-MSA-B, orange CdTe QDs-MSA-C and red CdTe QDs-MSA-D were 23.0%, 16.0%, 18.0% and 7.0%, respectively. Green, yellow, orange and red CdTe QDs were replaced every day and exposed to daily UV radiation for 12 h for seven consecutive days in summer with UV index signal integration ranging from 1894 to 2970. The rising dose of UV radiation led to the release of cadmium ions and the change in the size of individual QDs. The shifts were evident in absorption signals (shifts of the absorbance maxima of individual CdTe QDs-MSA were in the range of 6–79 nm), sulfhydryl (SH)-group signals (after UV exposure, the largest changes in the differential signal of the SH groups were observed in the orange, green, and yellow QDs, while in red QDs, there were almost no changes), fluorescence, and electrochemical signals. Yellow, orange and green QDs showed a stronger response to UV radiation than red ones.

show abstract

“…Interesting work was reported in which L-cysteine (Cys) capped CdTe QDs were prepared in an aqueous medium. This study suggested that the capping agent reduced cytotoxicity upon the basis of experiments involving HeLa cancer cell lines (Kim et al 2015). For cytotoxicity of CdSe/CdS QDs, it was paradoxically found that comparing toxicity based on particle concentrations was extremely difficult (Soenen et al 2015).…”

Section: Decreasing the Toxicity Of Qds In Biomedical Applicationsmentioning

confidence: 99%

Revisiting the cytotoxicity of quantum dots: an in-depth overview

et al. 2020

View full text Add to dashboard Cite

Recently, medical research has been shifting its focus to nanomedicine and nanotherapeutics in the pursuit of drug development research. Quantum dots (QDs) are a critical class of nanomaterials due to their unique properties, which include optical, electronic, and engineered biocompatibility in physiological environments. These properties have made QDs an attractive biomedical resource such that they have found application as both in vitro labeling and in vivo theranostic (therapydiagnostic) agents. Considerable research has been conducted exploring the suitability of QDs in theranostic applications, but the cytotoxicity of QDs remains an obstacle. Several types of QDs have been investigated over the past decades, which may be suitable for use in biomedical applications if the barrier of cytotoxicity can be resolved. This review attempts to report and analyze the cytotoxicity of the major QDs along with relevant related aspects.

show abstract

Highly fluorescent CdTe quantum dots with reduced cytotoxicity-A Robust biomarker

Cited by 37 publications

References 46 publications

Rapid Synthesis of Thiol-Co-Capped-CdTe/CdSe/ZnSe Core Shell-Shell Nanoparticles: Their Optical and Structural Morphology

Rapid Synthesis of Thiol-Co-Capped-CdTe/CdSe/ZnSe Core Shell-Shell Nanoparticles: Their Optical and Structural Morphology

Study of Physico-Chemical Changes of CdTe QDs after Their Exposure to Environmental Conditions

Revisiting the cytotoxicity of quantum dots: an in-depth overview

Contact Info

Product

Resources

About