Highly efficient synthesis of novel bio-based pentamethylene dicarbamate via carbonylation of pentanediamine with ethyl carbamate over well-defined titanium oxide catalysts

Abstract

Highly efficient synthesis of bio-based pentamethylene dicarbamate from pentanediamine and ethyl carbamate was successfully achieved over the well-defined TiO2 catalysts, which provides a green and sustainable way for the production of bio-based isocyanates or polyurethane.

Hydrogen Bond Promoted Methoxycarbonylation of Pentanediamine to Biobased Dicarbamate by Accelerating Proton Transfer

“…Carbamates are key intermediates in pharmaceutical and fine chemical syntheses; − additionally, they have recently become crucial in polyurethane production as an eco-friendly alternative to toxic phosgene. − As the key building blocks for polyurethane, N-substituted carbamates are used with diamines or diols to produce oligomers for self-supporting foam as well as for other applications. − Importantly, they serve as green and environmentally benign precursors for the phosgene-less synthesis of isocyanates via thermal decomposition. ,, PDA could be synthesized through whole-cell catalysis in which lysine is converted into PDA by the catalysis of lysine decarboxylase. The substrate l -lysine has been successfully commercialized by extracting from biomass, making it an ideal raw material for producing PDA.…”