Highly efficient and regioselective production of trisubstituted alkenes through heck couplings catalyzed by a palladium phosphinito PCP pincer complex

High‐Turnover Palladium Catalysts in Cross‐Coupling and Heck Chemistry: A Critical Overview

“…Thus, their reactions are usually performed at very high temperatures. [116] Relatively high TONs can be achieved in a number of standard couplings. [117] Deactivation of these catalysts by 1,4-dienes has been reported.…”

Recent Advances on the Chemistry of POCOP–Nickel Pincer Compounds

“…This later concept has led to the discovery of a vast variety of different pincer ligands beyond the traditional aromatic PCP backbone. One large step forward was provided by Morales-Morales and Jensen and by Bedford [44,45] in 2000 when they, independently, reported the synthesis of the first POCOP-phosphinite pincer systems (Fig. 2), thus providing a convenient answer to this synthetic problem.…”

Alkyl‐ and Arylthiolation of Aryl Halides Catalyzed by Fluorinated Bis‐Imino‐Nickel NNN Pincer Complexes [NiCl2{C5H3N‐2,6‐(CHNArf)2}]

“…[12] We believe that a robust complex used as catalyst may render a better performance in the alkyl-and arylthiolation of halobenzenes. Thus, following our continuous interest in the use of pincer type-compounds [13] for novel organic transformations and the use of aromatic fluorinated substituents [13] for the tuning of steric and electronic properties, we report our findings in the use of fluorinated bis-iminonickel(II) NNN pincer complexes [NiCl 2 {C 5 H 3 N-2,6-(CHNAr f ) 2 }] as efficient catalysts for the cross-coupling of (RS) 2 and halobenzenes. (2), C 6 H 3 -3,4-F 2 (3), C 6 H 3 -3,5-F 2 (4), C 6 H 2 -2,3,4-F 3 (5), C6H 2 -2,3,6-F 3 (6), C 6 H 2 -2,4,5-F 3 (7), C 6 H 2 -2,4,6-F 3 (8) in high yields.…”