Highly Effective Antiretroviral Therapy and Cerebral Aneurysms

Abstract

Classically, the death of patients infected with the human immunodeficiencyvirus (HIV) has been due to multiple causes, including incurable systemic infections, neurological disease and multisystem failure. With the advent of the highly effective antiretroviral therapies (HAART), the survival has been longerand processes that have traditionally not had enough time to play a role in the functional decline of HIV-infected patients are appearing. Although vascular complications in HIV-infected patients in use of HAARTs has been addressed in the literature, there has been limited discussions regarding the possiblerelationship between infection with HIV, use of HAART and the development of cerebral aneurysms. The aim of the present study is provide insight into the understanding of cerebrovascular complications, especially cerebral aneurysms, associated with the use of HAARTs in HIV-infected patients.