Highly dispersed nanoscale hydroxyapatite on cellulose nanofibers for bone regeneration

Yamaguchi, Kyohei; Prabakaran, Mayakrishnan; Ma, Ke; Xu, Gang; Chung, Ill Min; Um, In Chul; Gopiraman, Mayakrishnan; Kim, Ick Soo

doi:10.1016/j.matlet.2016.01.010

Cited by 43 publications

(22 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If implanted directly, it may dislocate within the tissue 20 . To eliminate such an undesired mobility, HA is usually mixed with natural or synthetic polymers, such as cellulose (Cel) and polyacrylamide (PAAm) [21][22][23][24] . Cel is the most abundant material in most plants and bacteria.…”

Section: Introductionmentioning

confidence: 99%

Cellular compatibility of nanocomposite scaffolds based on hydroxyapatite entrapped in cellulose network for bone repair

Beladi

Saber-Samandari

Saber‐Samandari

2017

Materials Science and Engineering: C

View full text Add to dashboard Cite

In the past few decades, artificial graft materials for bone tissue engineering have gained much importance. In this study, novel porous 3D nanocomposite scaffolds composed of polyacrylamide grafted cellulose and hydroxyapatite were proposed. They were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction analysis (XRD). The swelling behavior of the scaffolds was examined in both water and phosphate buffer saline (PBS) solution. The cytotoxicity of the scaffolds was determined by MTT assays on human fibroblast gum (HuGu) cells. Results showed that the nanocomposite scaffolds were highly porous with maximum porosity of 85.7% interconnected with a pore size of around 72-125μm. The results of cell culture experiments showed that the scaffolds extracts do not have cytotoxicity in any concentration. Obtained results suggested that the introduced scaffolds are comparable with the trabecular bone from the compositional, structural, and mechanical perspectives and have a great potential as a bone substitute.

show abstract

Section: Introductionmentioning

confidence: 99%

Cellular compatibility of nanocomposite scaffolds based on hydroxyapatite entrapped in cellulose network for bone repair

Beladi

Saber-Samandari

Saber‐Samandari

2017

Materials Science and Engineering: C

View full text Add to dashboard Cite

show abstract

“…Firstly, apparatus was washed with HCL (to sterilize) and then by deionized or double distilled water, thereafter while stirring, each chemical was added to 1000ml deionized water at 36.5 o C in the quantity as mentioned in the table 1 till order#8 and reagent 9 added slowly in quantity less than 1g to avoid increase in pH locally. After adjusting pH to 7.25 at a temperature of 36.5 o C the fluid was left for 1-2 days to be stable [19]. [20].…”

Section: Methodsmentioning

confidence: 99%

Fabrication of Cellulose Acetate/Cellulose-HA Composite Films for Bone Fixation

Fatima¹,

Khalid²,

Akram

et al. 2018

KEM

View full text Add to dashboard Cite

Bone is a rigid and constantly remodeling organ, a type of tissue which provides support and protects organs in the body, and together they form the skeleton [1]. Materials generally used for implants bear tissue rejection and produce toxins on degradation [2]. Our objective is to synthesize a biocompatible composite of Hydroxyapatite (HA) and Cellulose using Cellulose Acetate as a matrix which mimics the properties of natural bone that can be used for bone replacements. Bone is composed of calcium phosphate (HA) and collagen, which gives bone desired properties [3]. Hydroxyapatite is the inorganic mineral found in the bone and is preferred due to its mechanical properties, biocompatibility, slow degradation in physiological environment and bioactivity [4]. Cellulose, structural component in plants is similar in properties to collagen therefore the properties of cellulose [4], HA and cellulose acetate are exploited to achieve our results. The experimental procedure is divided into two major steps; extraction of cellulose microfibers (CMF) from cotton followed by dispersion of cellulose and HA in cellulose acetate then casting membranes of the composite.

show abstract

“…The polymer Nacarboxymethyl cellulose (Na-CMC) of plant origin is being widely used. It is used as a solutions stabilizer in oil production [1], as a binding agent in medicine [2][3][4], as a binding component of lithium-ion battery anode [5][6][7] in energy production. Water solutions of the polymer are a cheap medium for creating functional nano-sized additives, synthesized from metal powders [8].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of adhesion strength of protective coatings with Al powder by adhesion work of initial suspension towards metal surface

Antonova¹

2018

MATEC Web Conf.

View full text Add to dashboard Cite

The influence of energetic factors upon surface properties of suspensions on the basis of Na-CMC with aluminum powder, used to produce anticorrosion coatings, is revealed. It is shown that relative adhesion work, got by measuring the extent of suspensions surface strain and the angles of wetting the steel surface with suspensions, correlate with adhesion strength of coatings containing aluminum powder.

show abstract

Highly dispersed nanoscale hydroxyapatite on cellulose nanofibers for bone regeneration

Cited by 43 publications

References 23 publications

Cellular compatibility of nanocomposite scaffolds based on hydroxyapatite entrapped in cellulose network for bone repair

Cellular compatibility of nanocomposite scaffolds based on hydroxyapatite entrapped in cellulose network for bone repair

Fabrication of Cellulose Acetate/Cellulose-HA Composite Films for Bone Fixation

Evaluation of adhesion strength of protective coatings with Al powder by adhesion work of initial suspension towards metal surface

Contact Info

Product

Resources

About