Highly concentrated very long-chain PUFA obtainment by Urea complexation methodology

González‐Fernández, María José; Fabrikov, Dmitri; Lyashenko, Svetlana; Ferrón-Carrillo, Francisca; Guil‐Guerrero, José Luis

doi:10.1016/j.eti.2020.100736

Cited by 23 publications

(21 citation statements)

References 33 publications

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“…fatty acid ratio of 7:1 (González-Fernández et al, 2020). Other methods of concentrating PUFAs include SFE, molecular distillation, freezing crystallization, winterization and chromatography using a silver resin (Magallanes et al, 2019).…”

Section: Purification Of Epamentioning

confidence: 99%

“…The latter has a linear structure that can be trapped in the urea complex and crystallized upon cooling, while the remaining liquid is enriched in PUFAs and can be separated by filtration. The purity of EPA from Nannochloropsis oil was increased from 22.7% to 43% of TFA using the urea complexation method at an urea: fatty acid ratio of 7:1 (González‐Fernández et al, 2020). Other methods of concentrating PUFAs include SFE, molecular distillation, freezing crystallization, winterization and chromatography using a silver resin (Magallanes et al, 2019).…”

Section: Downstream Processing Strategies For the Valorization Of The...mentioning

confidence: 99%

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Sustainable production of eicosapentaenoic acid-rich oil from microalgae: Towards an algal biorefinery

Sivakumar

Sachin

Priyadarshini

et al. 2022

Journal of Applied Microbiology

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Utilization of sustainable natural resources such as microalgae has been considered for the production of biofuels, aquaculture feed, high‐value bioactives such as omega‐3 fatty acids, carotenoids, etc. Eicosapentaenoic acid (EPA) is an omega‐3 fatty acid present in fish oil, which is of physiological importance to both humans and fish. Marine microalgae are sustainable sources of lipid rich in EPA, and different species have been explored for the production of EPA as a single product. There has been a rising interest in the concept of a multi‐product biorefinery, focusing on the maximum valorization of the algal biomass. Targeting one or more value‐added compounds in a biorefinery scenario can improve the commercial viability of low‐value products such as triglycerides for biofuel. This approach has been viewed by technologists and experts as a sustainable and economically feasible possibility for the large‐scale production of microalgae for its potential applications in biodiesel and jet fuel production, nutraceuticals, animal and aquaculture feeds, etc. In this review paper, we describe the recent developments in the production of high‐value EPA‐rich oil from microalgae, emphasizing the upstream and downstream bioprocess techniques, and the advantages of considering an EPA‐rich oil‐based biorefinery.

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Section: Purification Of Epamentioning

confidence: 99%

Section: Downstream Processing Strategies For the Valorization Of The...mentioning

confidence: 99%

Sustainable production of eicosapentaenoic acid-rich oil from microalgae: Towards an algal biorefinery

Sivakumar

Sachin

Priyadarshini

et al. 2022

Journal of Applied Microbiology

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“…Urea fractionation can separate FAs according to their degree of unsaturation [ 77 ]. Triglycerides are hydrolyzed to give free fatty acids that are treated with urea and ethanol.…”

Section: Fractionation Techniquesmentioning

confidence: 99%

From Fish Waste to Value: An Overview of the Sustainable Recovery of Omega-3 for Food Supplements

Alfio¹,

Manzo²,

Micillo³

2021

Molecules

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The disposal of food waste is a current and pressing issue, urging novel solutions to implement sustainable waste management practices. Fish leftovers and their processing byproducts represent a significant portion of the original fish, and their disposal has a high environmental and economic impact. The utilization of waste as raw materials for the production of different classes of biofuels and high-value chemicals, a concept known as “biorefinery”, is gaining interest in a vision of circular economy and zero waste policies. In this context, an interesting route of valorization is the extraction of omega-3 fatty acids (ω-3 FAs) for nutraceutical application. These fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have received attention over the last decades due to their beneficial effects on human health. Their sustainable production is a key process for matching the increased market demand while reducing the pressure on marine ecosystems and lowering the impact of waste production. The high resale value of the products makes this waste a powerful tool that simultaneously protects the environment and benefits the global economy. This review aims to provide a complete overview of the sustainable exploitation of fish waste to recover ω-3 FAs for food supplement applications, covering composition, storage, and processing of the raw material.

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“…The solvent can be recovered and reused. The resulting polyunsaturated fatty acid has high purity, which is an ideal method for enriching various unsaturated fatty acids (María et al, 2020). The methods for producing CLAs include microbial fermentation, homogeneous catalytic isomerization of strong bases, and heterogeneous catalytic isomerization.…”

Section: Practical Applicationsmentioning

confidence: 99%

Application of Rh/MWCNT catalysts in the preparation of conjugated linoleic acid from linoleic acid

Cheng

Wang

et al. 2021

J. Food Process. Preserv.

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Conjugated linoleic acid (CLA) is a general term for a group of positions and geometric isomers containing conjugated double bonds in linoleic acid. The most biologically active isomers in CLA are c9,t11-CLA and t10,c12-CLA (Michael et al., 2001). Natural CLA is mainly derived from the biohydrogenation of rumen bacteria and found in rumen foods such as beef, milk, and dairy products (Shen et al., 2018). CLA is one of the essential fatty acids of the human body, but the human body cannot synthesize it, so it must be obtained from food. According to the research, CLA has the important effects of inhibiting obesity (Park & Pariza, 2007), inhibiting cardiovascular diseases, anticancer, and growth-promoting effects

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Highly concentrated very long-chain PUFA obtainment by Urea complexation methodology

Cited by 23 publications

References 33 publications

Sustainable production of eicosapentaenoic acid-rich oil from microalgae: Towards an algal biorefinery

Sustainable production of eicosapentaenoic acid-rich oil from microalgae: Towards an algal biorefinery

From Fish Waste to Value: An Overview of the Sustainable Recovery of Omega-3 for Food Supplements

Application of Rh/MWCNT catalysts in the preparation of conjugated linoleic acid from linoleic acid

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