Highly Accurate Profiling of Exosome Phenotypes Using Super-resolution Tricolor Fluorescence Co-localization
Jinxiu Wei,
Kai Zhu,
Tingyu Wang
et al.
Abstract:Exosomes contain a wealth of proteomic information, presenting
promising biomarkers for the noninvasive early diagnosis of diseases,
especially cancer. However, it remains a great challenge to accurately
and reliably distinguish exosomes secreted from different types of
cell lines. Fluorescence immunoassay is frequently used for exosome
detection. Nonspecific adsorption in immunoassays is unavoidable and
affects the reliability of assay results. Despite the fact that various
methods have been proposed to reduc… Show more
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