Highlights in gibberellin research: A tale of the dwarf and the slender

Abstract

It has been almost a century since biologically active gibberellin (GA) was isolated. Here, we give a historical overview of the early efforts in establishing the GA biosynthesis and catabolism pathway, characterizing the enzymes for GA metabolism, and elucidating their corresponding genes. We then highlight more recent studies that have identified the GA receptors and early GA signaling components (DELLA repressors and F-box activators), determined the molecular mechanism of DELLA-mediated transcription reprogramming, and revealed how DELLAs integrate multiple signaling pathways to regulate plant vegetative and reproductive development in response to internal and external cues. Finally, we discuss the GA transporters and their roles in GA-mediated plant development.

Chemical Driving the Subtype Selectivity of Phytohormone Receptors Is Beneficial for Crop Productivity

“…24 GA was first identified from Gibberella fujikuroi in 1935 and has been found to be widely present in fungi, algae and various plants. 25 The discovery of the first GA binding protein (GBP) was reported in dwarf pea epicotyls in 1974, using 3 H labeled GA 1 as a probe. 26 M. Ueguchi-Tanaka et al have compiled a list of 19 GBPs that are considered candidates for GA receptors.…”

Celebrating the American Society of Plant Biologists centennial anniversary: A compendium of review articles in plant biology

“…In “Light signaling in plants—a selective history,” Huq et al (2024) review the discovery and characterization of phytochrome and cryptochrome sensory photoreceptors. Shani et al (2024) cover all things gibberellin: biosynthesis, metabolism, perception, signaling, and transport in “Highlights in gibberellin research: A tale of the dwarf and the slender.” Gasperini and Howe (2024) then guide us through the “blurred distinction between classical phytohormones and other bioactive metabolites” using jasmonate as an example in their review “Phytohormones in a universe of regulatory metabolites: lessons from jasmonate.” Kim et al (2024) explore the convergence of signaling pathways in plant responses to dehydration and temperature changes in their review “Regulatory networks in plant responses to drought and cold stress,” with an eye toward engineering climate-resilient crops. Two reviews focus on aspects of plant reproduction.…”

Celebrating the American Society of Plant Biologists centennial anniversary: A compendium of review articles in plant biology

“…In Light signaling in plants—a selective history , Huq et al (2024) review the discovery and characterization of phytochrome and cryptochrome sensory photoreceptors. Shani et al (2024) cover all things gibberellin: biosynthesis, metabolism, perception, signaling, and transport in Highlights in gibberellin research: A tale of the dwarf and the slender . Gasperini and Howe (2024) then guide us through the “blurred distinction between classical phytohormones and other bioactive metabolites” using jasmonate as an example in their review Phytohormones in a universe of regulatory metabolites: Lessons from jasmonate .…”