Highlights and recent developments in food and drug allergy, and anaphylaxis in EAACI Journals (2017)

Eigenmann, Philippe; Akdiş, Cezmi A.; Bousquet, Jean; Grattan, Clive; Hoffmann‐Sommergruber, Karin; Hellings, Peter; Agache, Ioana

doi:10.1111/pai.12986

Cited by 9 publications

(11 citation statements)

References 63 publications

(112 reference statements)

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“…The diagnostic procedure depends on the drug involved and the type of DHR, IR or NIR. [62][63][64][65] Precise definitions and provision of background, in a standardized available questionnaire, are helpful to correctly classify DHRs. 5,66,67 Although in NSAID hypersensitivity, the current classification needs a revision 68,69 including new entities as blended reactions.…”

Section: Iag Nos Ismentioning

confidence: 99%

Recent developments and highlights in drug hypersensitivity

Mayorga

Fernandez

Montañez

et al. 2019

Allergy

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Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis and asthma with a significant increase in prevalence in both adults and paediatric population with new drugs included as culprit. For this, DHRs represent not only a health problem but also a significant financial burden for affected individuals and health systems. Mislabelling DHRs is showing to be a relevant problem for both, false label of drug allergic and false label of nonallergic. All this reinforces the need to improve accurate diagnostic approaches that allow an appropriate management.Moreover, there is a need for training both, nonallergist stakeholders and patients to improve the reaction identification and therefore decrease the mislabelling. The use of allergy cards has shown to be relevant to avoid the induction of DHRs due to the prescription of wrong medication.Recent developments over the last 2 years and highlights about risk factors, diagnostic approaches, mechanisms involved as well as prevention actions, and management have been reviewed. In these papers, it has been outlined the need for correct diagnosis and de-labelling of patients previously false-reported as allergic, which will improve the management and treatment of patients with DHRs. K E Y W O R D Sallergy diagnosis, allergy treatment, basic mechanisms, drug allergy, epidemiology | 2369

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Section: Iag Nos Ismentioning

confidence: 99%

Recent developments and highlights in drug hypersensitivity

Mayorga

Fernandez

Montañez

et al. 2019

Allergy

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“…4 However, optimal protocol (s) have not been standardized. 5,6 DPTs are generally started in daycare units (DCUs) and prolonged at home. Reactions that may occur during DPTs are easily controlled, and performing DPTs in DCUs is expensive and needlessly time-consuming.…”

Section: Safety and Cost Effectiveness Of Supervised Ambulatory Drug mentioning

confidence: 99%

Safety and cost effectiveness of supervised ambulatory drug provocation tests in children with mild non‐immediate reactions to beta‐lactams

Jaoui

Delalande

Siouti

et al. 2019

Allergy

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“…[5][6][7] Because of that, the diagnosis of BL hypersensitivity in children is still an important and hot topic. 8 Most information about approach and management on BL hypersensitivity in children is applied from available guidelines and consensus statement for adults. 4,9…”

Section: Introductionmentioning

confidence: 99%

What is new in beta‐lactam allergy in children?

Atanasković-Marković

2020

Pediatric Allergy Immunology

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This review highlights the novelties in understanding the underlying immunologic mechanisms of drug hypersensitivity reactions (DHRs) with special reference to beta‐lactams (BLs) in the pediatric population, as well as tiny changes in clinical classification and diagnosis of DHRs, in the last couple of years. BLs are still the most commonly prescribed and used antibiotics in children. Viral infections are very often in children, and they can provoke skin rashes which are difficult to differentiate from DHRs. The majority of children are incorrectly labeled as “allergic.” Therefore, allergy to BLs in children is overdiagnosed. These children often receive suboptimal treatment with second‐line broad‐spectrum antibiotics, which are less effective, more costly, and associated with an increased risk of antibiotic‐resistant infections. This prolongs hospitalization and thus more uses health care. The correct diagnosis of BL allergy in children is still an important and hot topic. This review has outlined the need for correct diagnosis of BL allergy in children and all the controversies encountered by pediatricians and pediatric allergists. It is also necessary to change the paradigm.

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Highlights and recent developments in food and drug allergy, and anaphylaxis in EAACI Journals (2017)

Cited by 9 publications

References 63 publications

Recent developments and highlights in drug hypersensitivity

Recent developments and highlights in drug hypersensitivity

Safety and cost effectiveness of supervised ambulatory drug provocation tests in children with mild non‐immediate reactions to beta‐lactams

What is new in beta‐lactam allergy in children?

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