Highlight report: co-cultures of hepatocytes and macrophages for hepatotoxicity testing

Abstract

may indeed improve in vitro hepatotoxicity testing. Limitations of the current study are that so far only one compound has been tested and that no primary cells could be used. Nevertheless, the study of Wewering et al. is of high interest and further studies are needed to gain deeper insight as to which degree hepatocyte-immune cell interactions can be simulated in vitro. References