Higher Immunoglobulin E Antibody Levels to Recombinant Fel D 1 in Cat-Allergic Children With Asthma Compared With Rhinoconjunctivitis

Abstract

PURPOSE OF THE STUDY. Because pet allergies are associated with asthma, the authors investigated whether highefficiency particulate-arresting (HEPA) filtration had any effect on reducing indoor allergens and bronchial hyperreactivity in children with asthma who were sensitized to cat and dog. STUDY POPULATION. A total of 30 children with asthma (age: 6-17 years) who were sensitized and exposed to cat and/or dog allergen(s) at home completed the study. The children did not have dust mite or mold sensitivities, and those being treated for asthma stayed on treatment throughout this time.