Higher hypertension prevalence, lower incidence, and aggressive treatment with decreasing mortality, cardiovascular, and cerebrovascular incidence in Taiwan from 2005 to 2010

Abstract

Hypertension continues to be an important public health concern because of its associated morbidity, mortality, and economic impact on society. The aims of this study are to compare the secular changes in age-stratified hypertension prevalence, incidence, co-morbidity, and 3 years of cardiovascular outcome in Taiwan in the years 2005 and 2010. We enrolled hypertensive individuals from the datasets of the Longitudinal Health Insurance Database (LHID) in 2005 and 2010 in Taiwan separately. We analyzed the hypertension prevalence, incidence, medication treatment, and associated morbidities. The risks of cardiovascular and cerebrovascular events and all-causes mortalities among the hypertensive individuals were evaluated in 3 years of follow-up. There was an increased prevalence of hypertension but decreased incidence of hypertension in those over 65 from 2005 to 2010. Dyslipidemia was the highest rate of co-morbidity in 2005 and 2010. The most frequent categories of anti-hypertensive agents prescribed was 1 or 2 for both 2005 and 2010. Calcium channel blockers were the most common anti-hypertensive agents prescribed, followed by Angiotensin converting enzyme inhibitors/Angiotensin receptor blockers. After 3 years of follow-up, the risks of coronary artery disease (CAD), cerebrovascular diseases (CVD) as well as death were less in 2010 than in 2005 in Taiwan. Our study showed that hypertension individuals had an increased prevalence, younger age, decreased incidence, increased medication treatment associated with decreased the CAD, CVD, and mortalities in 2010 compared to 2005 in Taiwan.

Management of Hypertension in the Asia-Pacific Region: A Structured Review

“…CCBs and RAAS inhibitors (either ACEi or ARBs) were the most prescribed antihypertensive therapies in Taiwan, according to an analysis of the nationwide Longitudinal Health Database, which included 219,425 patients with hypertension [ 119 ].…”

Effects of Aerobic Walking on Memory, Subjective Cognitive Complaints, and Brain-Derived Neurotrophic Factor Among Older Hypertensive Women

“…The inclusion criteria were as follows: (1) age 60–80 years, (2) diagnosed with hypertension for at least 6 months, and (3) self-reported indications of problems with memory or thinking skills . The minimum age of 60 was selected because of the high prevalence of hypertension in older adults (Liao et al, 2020). The maximum age of 80 was selected because, in Taiwan, about 20% of those over age 80 has dementia (Taiwan Alzheimer Disease Association, 2022).…”

“…The prevalence of hypertension in older persons has increased in recent years (Pan et al, 2020). The prevalence of hypertension in adult women in one study was 25.4%, but it rose to over 50% in women over age 60 (Chiou et al, 2013;Liao et al, 2020). The high risk of cognitive impairment, including dementia, in older women with hypertension highlights the need to identify effective ways to reduce the burden of future cognitive decline.…”

Association between cognitive function and self‐reported antihypertensive medication adherence among middle‐aged and older hypertensive women

“…Hypertension is a burden on global health care because of its association with mortality, morbidity and socio‐economic impacts (Liao et al, 2020; Maïer & Kubis, 2019). The prevalence of hypertension worldwide is 20%–30%, and the prevalence of hypertension is increasing in the Asia‐Pacific region (Mills et al, 2016).…”