The goal of this paper is to set up the general framework of higher‐dimensional Heegaard Floer homology, define the contact class, and use it to give an obstruction to the Liouville fillability of a contact manifold and a sufficient condition for the Weinstein conjecture to hold. We discuss several classes of examples including those coming from analyzing a close cousin of symplectic Khovanov homology and the analog of the Plamenevskaya invariant of transverse links.