1985
DOI: 10.1515/znc-1985-1-216
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Higher Cardol Homologues (5-Alkenylresorcinols) from Rye Affect the Red Cell Membrane-Water Transport

Abstract: The influence o f 5-heptadecenylresorcinol and total rye 5-alkenylresorcinols isolated from rye grains on the red blood cell water perm eability was studied using osm otic shrinkage experim ents performed in 300 m M sucrose. The studied com pounds induced significant increase o f erythro cyte water permeability. The threshold concentration needed for the increase o f water per meability was in an order o f 10_ 6 m ol/l. The temperature dependence o f the observed process showed the discontinuity which was rela… Show more

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Cited by 13 publications
(2 citation statements)
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“…Phenolic lipids (especially resorcinolic lipids) are indicated for the prevention and/or treatment of cancer. The amphiphilic property of these compounds, which is attributed to the presence of non-isoprenoid side chains bound to the hydroxybenzene ring, permits their interaction with the lipid bilayer [ 4 6 ], the formation of liposomes [ 7 ], protection against oxidative stress [ 8 ] and the inhibition of bacterial [ 9 11 ] and tumor cell growth [ 12 , 13 ]. Particularly interesting are phenolic lipids of the cytosporone class, which present allelopathic activity [ 14 ] and can interact with the orphan nuclear receptor Nur77, triggering apoptosis [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…Phenolic lipids (especially resorcinolic lipids) are indicated for the prevention and/or treatment of cancer. The amphiphilic property of these compounds, which is attributed to the presence of non-isoprenoid side chains bound to the hydroxybenzene ring, permits their interaction with the lipid bilayer [ 4 6 ], the formation of liposomes [ 7 ], protection against oxidative stress [ 8 ] and the inhibition of bacterial [ 9 11 ] and tumor cell growth [ 12 , 13 ]. Particularly interesting are phenolic lipids of the cytosporone class, which present allelopathic activity [ 14 ] and can interact with the orphan nuclear receptor Nur77, triggering apoptosis [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…If added before phospholipid vesicles are formed, ARs showed a stabilizing effect on phospholipid bilayers. The membrane becomes more resistant to the permeation of small solutes, such as water, ions, and glucose (9)(10)(11)(12), and vesicles are more resistant to osmotic stress (13).…”
Section: Introductionmentioning
confidence: 99%