Higher cardiorespiratory fitness predicts long-term survival in patients with heart failure and preserved ejection fraction: the Henry Ford Exercise Testing (FIT) Project

Orimoloye, Olusola A.; Kambhampati, Swetha; Hicks, Albert J.; Rifai, Mahmoud Al; Silverman, Michael G.; Whelton, Seamus P.; Qureshi, Waqas; Ehrman, Jonathan K.; Keteyian, Steven J.; Brawner, Clinton A.; Dardari, Zeina; Al‐Mallah, Mouaz H.; Blaha, Michael J.

doi:10.5114/aoms.2019.83290

Cited by 19 publications

(12 citation statements)

References 33 publications

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“…These data indicate that drug treatment of heart failure is still inadequate, however can be also result of overreporting CHF by study subjects. On the other hand our results on the use of ACE-I and beta-blockers were similar to another study in CHF patients, where beta receptor blockers were used by less than 70% of patients [23].…”

Section: Drug Treatmentsupporting

confidence: 89%

Prevalence of self-reported heart failure in the adult Polish population: results of the NATPOL 2011 study

Puch-Walczak¹,

Bandosz²,

Grodzicki³

et al. 2022

Polish Archives of Internal Medicine

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The growing epidemic of chronic heart failure (CHF) has been highlighted by the World Health Organization and the European Society of Cardiology. There are only few studies assessing the epidemiology of CHF in Europe and there are no such studies in the general population in Poland, which is one of the countries representing Central and Eastern Europe -a region of high cardiovascular risk. In this paper we have discussed current prevalence of heart failure in Poland. To assess the prevalence of CHF we asked about an earlier diagnosis of CHF. In order to verify the diagnosis, we checked the coding of CHF-related services in the NHF database. Previous diagnosis of CHF was reported in 4,3% of NATPOL 2011 study participants, and in 2,4% the diagnosis was confirmed in NHS database.Please note that NATPOL 2011 was carried out in the age group 18-79 and the prevalence of heart failure increases with age and we expect the highest prevalence in the seniors (>80 years of age). However, this is more than the previous estimates.

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Section: Drug Treatmentsupporting

confidence: 89%

Prevalence of self-reported heart failure in the adult Polish population: results of the NATPOL 2011 study

Puch-Walczak¹,

Bandosz²,

Grodzicki³

et al. 2022

Polish Archives of Internal Medicine

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“…Similar findings were also observed in European populations [2,3]. Despite important advances in diagnosis and management over the past two decades [4], chronic HF patients still have a poor prognosis [1,[5][6][7][8] with a mortality around 50% at five years [9].…”

Section: Introductionsupporting

confidence: 65%

Prognostic value of lung ultrasonography and bioimpedance spectroscopy in patients with heart failure and reduced ejection fraction

Siriopol

Mihaila

et al. 2020

Arch Med Sci

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IntroductionChronic heart failure (HF) represents a major global public health problem, and despite significant advances in diagnosis and management over the past two decades, HF patients still have a poor prognosis. The aim of the study was to evaluate the relationship between lung congestion, as assessed by lung ultrasonography (LUS), bioimpedance spectroscopy, body fluid compartments, and echocardiographic parameters, and to determine the effect of these associations on all-cause mortality in HF patients.Material and methodsEligible patients with a left ventricular ejection fraction (LVEF) below 45% were identified via daily echocardiography assessments. Lung ultrasonography was performed with patients in the supine position, for a total of 28 sites per complete examination. The extracellular water (ECW) was determined using a BIS device.ResultsOur study included 122 patients (67.2% males) with a mean age of 67.2 years. In the multivariable linear regression analysis, including all the univariable predictors of lung congestion, only New York Heart Association (NYHA) class, ECW, estimated glomerular filtration rate (eGFR), and LVEF levels maintained an independent association with the number of B-lines. During the follow-up, 33 patients died. In multivariable Cox analysis, a B-line number of at least 15 remained significantly associated with all-cause mortality, independently of age, sex, diabetes, LVEF, estimated glomerular filtration rate, C-reactive protein, N-terminal pro-brain natriuretic peptide, or ECW values (adjusted HR = 3.84, 95% CI: 1.12–13.09).ConclusionsWe show for the first time in HF patients that pulmonary congestion, as assessed by LUS, is associated with the severity of NYHA class, LVEF, eGFR, and ECW, and it identifies those at increased risk of death.

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“…For example, although the prevalence of pneumonia was similar after matching, it is possible that pneumonia in the longer LoS group was more severe or complicated. A longer LoS may also lead to 12-month HR (95% CI) = 1.16 (1.06-1.27), p = 0.002 a higher prevalence of unmeasured confounders such as loss of function, strength, coordination, and mobility [28,29].…”

Section: Discussionmentioning

confidence: 99%

Length of stay and readmission in older adults hospitalized for heart failure

et al. 2021

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Introduction: Hospital length of stay (LoS) and hospital readmissions are metrics of healthcare performance. We examined the association between these two metrics in older patients hospitalized with decompensated heart failure (HF). Material and methods: Eight thousand and forty-nine patients hospitalized for HF in 106 U.S. hospitals had a median LoS of 5 days; among them, 3777 had a LoS > 5 days. Using propensity scores for LoS > 5 days, we assembled 2723 pairs of patients with LoS 1-5 vs. > 5 days. The matched cohort of 5446 patients was balanced on 40 baseline characteristics. We repeated the above process in 7045 patients after excluding those with LoS > 10 days, thus assembling a second matched cohort of 2399 pairs of patients with LoS 1-5 vs. 6-10 days. Hazard ratios (HR) and 95% confidence intervals (CI) for outcomes associated with longer LoS were estimated in matched cohorts. Results: In the primary matched cohort (n = 5446), LoS > 5 days was associated with a higher risk of all-cause readmission at 30 days (HR = 1.16; 95% CI: 1.04-1.31; p = 0.010), but not during longer follow-up. A longer LoS was also associated with a higher risk of mortality during 8.8 years of follow-up (HR = 1.13; 95% CI: 1.06-1.21; p < 0.001). LoS had no association with HF readmission. Similar associations were observed among the matched sensitivity cohort (n = 4798) that excluded patients with LoS > 10 days. Conclusions: In propensity score-matched balanced cohorts of patients with HF, a longer LoS was independently associated with poor outcomes, which persisted when LoS > 10 days were excluded.

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Higher cardiorespiratory fitness predicts long-term survival in patients with heart failure and preserved ejection fraction: the Henry Ford Exercise Testing (FIT) Project

Cited by 19 publications

References 33 publications

Prevalence of self-reported heart failure in the adult Polish population: results of the NATPOL 2011 study

Prevalence of self-reported heart failure in the adult Polish population: results of the NATPOL 2011 study

Prognostic value of lung ultrasonography and bioimpedance spectroscopy in patients with heart failure and reduced ejection fraction

Length of stay and readmission in older adults hospitalized for heart failure

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