“…In order to counter these disadvantages, the synthesis of 1,3,6,8-tetrakis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrene was reported by Yamada and coworkers by nickel catalyzed direct borylation achieving a yield of 74% in two days 26 . Furthermore, synthesis of 1,2,4,5-tetrakis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene was reported by Wagner and coworkers with an overall yield of 64%; however, their synthetic process was a two-step reaction system achieving only partial borylation and the use of highly pyrophoric and toxic reagents such as n-butyllithium and Grignard reagents 27 . Both Aubert et al and Gandon et al utilized cobalt-catalyzed [2+2+2] cycloaddition of ethynyl pinacol borate to yield a mixture of 2,2′,2″-(benzene-1,2,4-triyl)tris(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) and 1,3,5-tris(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene with a yield of 63% 28 29 .…”