High Yield of Supergiant Vesicles on Glyoxylic Acid Modified Aluminum Electrode

Abstract

Supergiant vesicles are useful for investigating the interactions between lipid memebranes and collodial particles or macromolecules. Producing supergiant vesicles using the electroformation method lead to extraordinary findings in this work. The glyoxylic acid modified aluminum (GA-Al) electrode was prepared by the electro-reduction in an oxalic acid solution. High yield of supergiant vesicles with diameters >100 lm are successfully formed on a GA-Al electrode under an alternative current (AC) electric field. In contrast to platinum and indium tin oxide, which have been mainly used so far, this GA-Al electrode is preferable for the electroformation of egg phosphatidylcholine (EggPC) supergiant vesicles.