High-Volume Calcium Hydroxylapatite Filler to the Lower One-Third of the Face

Effectiveness and Safety of Calcium Hydroxylapatite With Lidocaine for Improving Jawline Contour

“…3,4 To reestablish or correct optimal jawline contour, a soft tissue filler with high elasticity and viscosity offers the best volumizing capacity.2 Over the last decade, multiple published reports have demonstrated that fillers, such as calcium hydroxylapatite (CaHA; Radiesse ® , Merz North America, Raleigh, NC, USA) improve the appearance of the aging jawline. [4][5][6][7][8][9][10][11] The available A. Moradi, J.B. Green, J.L. Cohen, et al literature supports both the effectiveness and safety of CaHA for injection along the jawline, from the mentum to the mandibular angle.…”

“…Multiple authors have reported favorable results 6-and 12-months after product placement, noting both investigator and patient satisfaction. [6][7][8][11][12] Few procedure-related adverse events, such as pain, erythema, edema, and bruising, were reported -most of which were mild and resolved quickly without intervention. Overall, the reported safety profile of CaHA for improving jawline contour is favorable and comparable to other established treatment indications.…”

Safety and effectiveness of injection of calcium hydroxylapatite via blunt cannula compared to injection by needle for correction of nasolabial folds

“…The semi‐permanent dermal filler calcium hydroxylapatite (CaHA; Radiesse Dermal Filler [RDF]; Merz Aesthetics, Greensboro, NC, USA) was FDA‐approved in 2006 for treatment of facial lines and nasolabial folds (NLF), and has since been used widely and with considerable efficacy to successfully correct NLF . Pain and the possibility of vascular occlusion remain two concerns for both patients and physicians when considering injections of CaHA.…”

Six-Month, Double-Blind, Randomized, Split-Face Study to Compare the Efficacy and Safety of Calcium Hydroxylapatite (CaHA) Mixed with Lidocaine and CaHA Alone for Correction of Nasolabial Fold Wrinkles

“…Nonsurgical, minimally invasive cosmetic treatments are increasing at a substantial rate. The dermal filler calcium hydroxylapatite (CaHA; Radiesse Dermal Filler (RDF), BioForm Medical Inc, San Mateo, CA) is a synthetic material approved by the Food and Drug Administration (FDA) in late 2006 for treating facial lines and wrinkles such as nasolabial folds (NLFs) 1 . CaHA has been used since 2002 with an excellent safety and side‐effect profile for patients with human immunodeficiency virus–associated lipoatrophy and for reducing facial wrinkles and correction of the NLFs 2–4 .…”

“…The dermal filler calcium hydroxylapatite (CaHA; Radiesse Dermal Filler (RDF), BioForm Medical Inc, San Mateo, CA) is a synthetic material approved by the Food and Drug Administration (FDA) in late 2006 for treating facial lines and wrinkles such as nasolabial folds (NLFs). 1 CaHA has been used since 2002 with an excellent safety and side-effect profile for patients with human immunodeficiency virusassociated lipoatrophy and for reducing facial wrinkles and correction of the NLFs. [2][3][4] The FDA has also approved CaHA for a variety of indications such as radiographic tissue marking, vocal cord insufficiency, oral and maxillofacial augmentation, correction of NLF wrinkles, and urinary incontinence.…”