High-throughput viscosity determinations

Abstract

A new high-throughput viscosimeter device was designed, built, and tested allowing measurement of the viscosity of 100 different solutions in a single experiment using the falling sphere approach. Using the corrected Stokes' law, viscosities obtained by the HT device were compared to viscosities of the same solutions obtained on a conventional viscosimeter and showed excellent correlation. The theoretical set of data, correlated with Reynolds numbers, and the viscosities obtained for each sample showed very good correlation with the experimental data, demonstrating the robustness of the device.

Design of an extreme ultraviolet spectrometer suite to characterize rapidly heated solid matter

“…Previous inferences of temperature from the emission in this region have shown significant departures between the temperature observed in the continuum and electronic line ratios in timeintegrated XUV spectrum measurements. 11,12 The streaked data here show that the continuum and line radiation occur at substantially different times in the expansion. This may explain the discrepancy between the temperature inferred from line emission and continuum emission.…”

Automated pipetting robot for proxy high-throughput viscometry of Newtonian fluids

“…Other efforts in this area have focused on developing microuidic-based viscometers. [21][22][23][24][25] However, such methods are unable to achieve the level of throughput needed for rapid screening of large numbers of samples, for instance, in formulation development. As an illustrative example, two academic studies carried out with an industrial partner generated 224 and 338 samples, respectively, so a benchmark would be an instrument capable of characterizing hundreds of samples within a month.…”

Viscometer using drag force measurements

“…1 The viscosity reflects the resistance of a fluid to flow under an applied shear stress and many different types of viscometers have been developed to achieve this measurement. They may be classified in four main families: capillary viscometers, [2][3][4] rotational or sliding viscometers, 5, 6 falling spheres 7,8 or slender objects, 9 and vibrational viscometers. 10 In the present study, a viscometer based on the measurement of the friction force exerted by a flowing fluid is presented.…”