High-throughput sequencing analysis of the characteristics of the gut microbiota in aged patients with sarcopenia

Association of skeletal muscle function, quantity, and quality with gut microbiota in Japanese adults: A cross‐sectional study

“…To our knowledge, no previous studies have reported an association between relative abundance of Bacteroides and skeletal muscle power, although several previous studies have reported a potential association between Bacteroides and sarcopenia or skeletal muscle phenotype. In a recent report comparing sarcopenia and control groups at the genus level, the relative abundance of Bacteroides , Faecalibacterium , Fusobacterium , and Prevotella 9 were significantly lower in the sarcopenia group 34 . An aerobic exercise training intervention for older Japanese women increased the relative abundance of Bacteroides and was positively correlated with walking performance 35 .…”

“…a recent report comparing sarcopenia and control groups at the genus level, the relative abundance of Bacteroides, Faecalibacterium, Fusobacterium, and Prevotella 9 were significantly lower in the sarcopenia group. 34 An aerobic exercise training intervention for older Japanese women increased the relative abundance of Bacteroides and was positively correlated with walking performance. 35 Additionally, a study of Japanese longdistance runners found an association between Bacteroides uniformis and endurance exercise performance, with α-cyclodextrin supplementation increasing B. uniformis and improving endurance exercise performance.…”

d-Pinitol Improves Diabetic Sarcopenia by Regulation of the Gut Microbiome, Metabolome, and Proteome in STZ-Induced SAMP8 Mice

“…30 Enterobacteriaceae was negatively correlated with muscle mass. 16 Lachnospiraceae, a normal gut microbiota, was significant diminished in cancer cachexia mice. 31 Our results suggested that the regulation of gut microbiota by DP partly contributed to the improvement of DS.…”

“…Lee et al reported that the content of Parabacteroides and Enterobacteriaceae significantly increased among sarcopenic patients . Enterobacteriaceae was negatively correlated with muscle mass . Lachnospiraceae, a normal gut microbiota, was significant diminished in cancer cachexia mice .…”

“…Recent investigations have unveiled a significant correlation between gut microbiota and sarcopenia, which plays a crucial role in the maintenance of skeletal muscle homeostasis. It has been reported that gut microbiota affects muscle protein synthesis by regulating the host’s inflammatory response, oxidative stress, mitochondrial function, nutrient absorption and hormone levels. − Moreover, gut microbiota plays an important part in the pathogenesis of diabetes . Therefore, gut microbiota emerge as an important factor in the pathogenesis of DS.…”