High throughput separation of blood cells by using hydrodynamics and magnetophoresis

Seo, Hye-Kyoung; Kang, Dong Heon; Ahn, Hye Rin; Kim, H. O.; Kim, Y. J.

doi:10.1109/transducers.2011.5969459

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…The particles get separated through their presence of semi-permeable membrane. In this work, hydrodynamic cell trapping method is used to make cells move along the filters and get laterally trapped in the bottom channel [16]. Using COMSOL Multiphysics, the microchannel has been designed using Computational fluid dynamics (CFD) module, simulated and analyzed [25].…”

Section: Blood Flow Separator Design In Passivementioning

confidence: 99%

Blood Flow Separator Design in Passive Lab-On-Chip Device

2019

IJITEE

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Nowadays, most of the clinical analytical tests are performed by separating the blood particles and it is exclusively used to diagnose the diseases in the medical field. There are various techniques which can be done through separating the particles, yet there are ways to go further for making the separation of particles efficient. Therefore, an on-chip integrated microfluidic device is required for separating the blood particles. The particle separation can be achieved by using porosity method which comes under the filtration techniques. The designed device consists of an inlet and an outlet reservoir. The device has a top channel and bottom channel for the blood flow where the filters are placed at the middle. By this way of filtration, it can easily separate normal and abnormal blood particles. From the whole blood sample, the particles are trapped by using hydrodynamics trapping method. The passive device is designed by COMSOL Multiphysics software and design results are presented

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Section: Blood Flow Separator Design In Passivementioning

confidence: 99%

Blood Flow Separator Design in Passive Lab-On-Chip Device

2019

IJITEE

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“…In general, cell separation technology can be classified into active separation and passive separation. Active separation uses external dielectric [1], magnetic [2,3], acoustic [4] or optical [5] forces to separate the particles. Compared with active separation, passive separation using pore-size-based filtration becomes more and more favorable because it is a label free, fast and high throughput method [6].…”

Section: Introductionmentioning

confidence: 99%

A continuously tunable size-based filter

Chang

Chen

et al. 2013

2013 Transducers &Amp; Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems

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In this paper we present a MEMS filter with continuously tunable pore size using a mirosieve-couple structure. The shape of the pore can be rectangular or square, while the size of the pore can be continuously tuned from a few microns to 200 microns dynamically. As far as we know, this is the largest tunable range among all the reported cell or microparticle sorters. The functionality of the tunable pore filter is validated using microbeads.

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High throughput separation of blood cells by using hydrodynamics and magnetophoresis

Cited by 2 publications

References 12 publications

Blood Flow Separator Design in Passive Lab-On-Chip Device

Blood Flow Separator Design in Passive Lab-On-Chip Device

A continuously tunable size-based filter

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