“…They also cause adverse effects on human health, such as respiratory system inactivation (Heidari & Asoodeh, 2019), loss of hair cells (responsible for balance), neurobehavioral abnormalities, decreased hearing, altered serotonin levels, and corneal opacity (Saldanha-Ruiz, et al, 2012). However, nitriles are widely used as intermediates in organic synthesis reactions (Chmura, et al, 2008;Santos, et al, 2021) such as hydrolysis (Mehtra, et al, 2017;Zhan, et al, 2018) and cycloaddition reactions (Umemoto, et al, 2020). They are also used as ingredients for obtaining plastics (An, et al, 2020), synthetic rubbers (Xiao, et al, 2019), and polymers (Lai et al, 2020), in addition to herbicides and pesticides (An, et al, 2018).…”