High-Throughput Nanoparticle Catalysis: Partial Oxidation of Propylene

Abstract

Partial oxidation of propylene was investigated at 1 atm pressure over Rh/TiO(2) catalysts as a function of reaction temperature, metal loading and particle size using high-throughput methods. Catalysts were prepared by ablating thin sheets of pure rhodium metal using an excimer laser and by collecting the nanoparticles created on the external surfaces of TiO(2) pellets that were placed inside the ablation plume. Rh nanoparticles before the experiments were characterized by transmission electron microscopy (TEM) by collecting them on carbon film. Catalyst evaluations were performed using a high-throughput array channel microreactor system coupled to quadrupole mass spectrometry (MS) and gas chromatography (GC). The reaction conditions were 23% C(3)H(6), 20% O(2) and the balance helium in the feed, 20,000 h(-1) GHSV and a temperature range of 250-325 degrees C. The reaction products included primarily acetone (AT) and to a lesser degree propionaldehyde (PaL) as the C(3) products, together with deep oxidation products COx.

Epoxidation of Propene by High-Throughput Screening Method Over Combinatorially Prepared Cu Catalysts Supported on High and Low Surface Area Silica

“…However in our study, 20 catalyst candidates were tested in one screening experiment and one data point was obtained *3 min for one catalyst. In the array microreactor, reactant gases flow over the flat surfaces of catalyst powder which are individually isolated within reactor channels; the flow regime is similar to that of a monolithic reactor [41]. All experiments were performed using 5 mg of catalyst under atmospheric pressure and at a gas hourly space velocity (GHSV) of 20,000 h -1 , representing a differential reactor condition.…”

“…binary, ternary and higher order combinations of metals as well as a large variety of support materials, call for the application of combinatorial or high-throughput heterogeneous catalysis tools and methods. Senkan and co-workers [38][39][40][41][42] made pioneering contributions to this field through the development of novel high-throughput catalyst preparation and screening tools. In particular, they developed array channel micro-reactors to rapidly screen a large number of catalytic materials in parallel [38,39].…”

New Catalytic Materials for the Direct Epoxidation of Propylene by Oxygen: Application of High-Throughput Pulsed Laser Ablation

“…binary, ternary and higher order combinations of metals as well as a large variety of support materials, call for the application of combinatorial or high throughput heterogeneous catalysis tools and methods. Our laboratories made pioneering contributions to this field through the development of novel high-throughput catalyst preparation and screening tools [18][19][20][21][22]. In particular, we developed array channel micro-reactors to rapidly screen a large numbers of catalytic materials in parallel [18,19].…”

“…In particular, we developed array channel micro-reactors to rapidly screen a large numbers of catalytic materials in parallel [18,19]. In addition, we coupled these array reactors to laser spectroscopy [18], photoionization detection (PID) [18], mass spectrometry [20], and fast gas chromatography [21]. Recently, we also developed a high-throughput pulsed laser ablation (HT-PLA) system for the synthesis of uniformly sized single-and multi-metallic nanoparticles for catalytic applications [22].…”

Nanocombinatorial Chemistry in Nanomaterial Discovery and Nanomedicine

“…利用组合化学 技术可以在短时间内实现大批量化合物的合成以及筛 选, 不仅可以大大提高化合物的合成效率, 还缩短了研 究周期以及降低实验成本. 目前, 组合化学已经在研发 新型药物 [1] 、催化剂 [2] 、聚合物 [3] 和新农药 [4] 等领域中得 到了广泛应用.…”