2022
DOI: 10.1038/s41598-022-13575-6
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High-throughput metabolomics reveals dysregulation of hydrophobic metabolomes in cancer cell lines by Eleusine indica

Abstract: Eleusine indica, which is used in traditional medicine, exhibits antiproliferative activity against several cancer cell lines. However, metabolomic studies to evaluate the metabolite changes induced by E. indica in cancer cells are still lacking. The present study investigated the anticancer effects of a root fraction of E. indica (R-S5-C1-H1) on H1299, MCF-7, and SK-HEP-1 cell lines and analyzed metabolic changes in the treated cancer cells using ultra-high-performance liquid chromatography high-resolution ma… Show more

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“…(Solanacae) for piles. From several recent scientific investigations, exhibited antioxidant, antidiabetic, antibacterial, anticonvulsant, anti-inflammatory, hepatoprotective, antipyretic, analgesic, etc., activities (Dorce et al, 2017;Ogbole et al, 2027;Puah et al, 2022). In addition, a few active phytochemicals, like hexanoic acid, sioschaftoside, sitosterol, stigasterol, isovitexin, vitexin, coumatin, etc., have been identified through column-chromatography, gas chromatography-mass spectrometry (GCMS), and liquid chromatography-mass spectrometry (LCMS) approaches (Ong et al, 2016;Sukor et al, 2023).…”
Section: Introductionmentioning
confidence: 99%
“…(Solanacae) for piles. From several recent scientific investigations, exhibited antioxidant, antidiabetic, antibacterial, anticonvulsant, anti-inflammatory, hepatoprotective, antipyretic, analgesic, etc., activities (Dorce et al, 2017;Ogbole et al, 2027;Puah et al, 2022). In addition, a few active phytochemicals, like hexanoic acid, sioschaftoside, sitosterol, stigasterol, isovitexin, vitexin, coumatin, etc., have been identified through column-chromatography, gas chromatography-mass spectrometry (GCMS), and liquid chromatography-mass spectrometry (LCMS) approaches (Ong et al, 2016;Sukor et al, 2023).…”
Section: Introductionmentioning
confidence: 99%