High-throughput experimentation in catalyst testing and in kinetic studies for heterogeneous catalysis

Six-flow operations for catalyst development in Fischer-Tropsch synthesis: Bridging the gap between high-throughput experimentation and extensive product evaluation

“…Variances such as those in packing the catalyst beds, inhomogeneity in a catalyst batch, etc., may significantly contribute to experimental errors in addition to other sources (e.g., analytical, mass and flow measurements, etc.). 10 The FTS reaction is highly exothermic 22 and the aforementioned catalysts' performance results suggest that small differences in heat dissipation from…”

“…We were among the first research groups that proposed the concept of such high-throughput experimentation, under realistic FTS process conditions. 2,[10][11][12] To date high-throughput FTS setups with up to 64 parallel reactors are reported and marketed. 13 Although high-throughput experimental setups are very suitable for exploratory screening of catalysts, they are often limited to analysis of the gas phase products.…”

Microreactor technology and process miniaturization for catalytic reactions—A perspective on recent developments and emerging technologies

“…The field of combinatorial chemistry as applied to catalysts was still in its infancy when the first wave of microreactors were being built more than 10 years ago, but it was apparent even then that massively parallel testing of catalysts favors smaller reactor sizes (Brummer et al, 2003;Moulijn et al, 2003;Stankiewicz and Moulijn, 2000). Although there are many screening techniques that do not use microreactors per se, one will eventually be needed at some stage for catalyst performance evaluation.…”

Microkinetic modeling as a tool in catalyst discovery

“…Recently the initial search for catalyst candidates has been speeded up by combinatorial methods and parallel screening [7]. The search for a catalyst candidate, using the combinatorial method, is based on testing small amounts of samples of many different compositions.…”